![](/images/graphics-bg.png)
Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris
المؤلفون المشاركون
Demirok, Ahmet
Yildirim, Yusuf
Olcucu, Onur
Alagoz, Cengiz
Demircan, Ali
Basci, Abdurrahman
Kutlubay, Zekayi
Agca, Alper
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-11-27
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Purpose.
We report the effect of isotretinoin on corneal topography, corneal thickness, and biomechanical parameters in patients with acne vulgaris.
Method.
Fifty-four eyes of 54 patients who received oral isotretinoin for treatment of acne vulgaris were evaluated.
All patients underwent a corneal topographical evaluation with a Scheimpflug camera combined with Placido-disk (Sirius), ultrasonic pachymetry measurements, and corneal biomechanical evaluation with an ocular response analyzer at baseline, in the 1st, 3rd, and 6th months of treatment, and 6 months after isotretinoin discontinuation.
Results.
The thinnest corneal thickness measured with Sirius differed significantly in the 1st, 3rd, and 6th months compared with the baseline measurement; there was no significant change in ultrasonic central corneal thickness measurements and biomechanical parameters (corneal hysteresis and corneal resistance factor) throughout the study.
Average simulated keratometry and surface asymmetry index increased significantly only in the first month of treatment according to the baseline.
All changes disappeared 6 months after the end of treatment.
Conclusion.
Basal tear secretion and corneal morphologic properties were significantly influenced during the systemic isotretinoin treatment and the changes were reversible after discontinuation.
No statistical important biomechanical differences were found to be induced by isotretinoin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yildirim, Yusuf& Olcucu, Onur& Agca, Alper& Alagoz, Cengiz& Demircan, Ali& Basci, Abdurrahman…[et al.]. 2014. Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris. Journal of Ophthalmology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042597
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yildirim, Yusuf…[et al.]. Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris. Journal of Ophthalmology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042597
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yildirim, Yusuf& Olcucu, Onur& Agca, Alper& Alagoz, Cengiz& Demircan, Ali& Basci, Abdurrahman…[et al.]. Evaluation of Corneal Topography and Biomechanical Parameters after Use of Systemic Isotretinoin in Acne Vulgaris. Journal of Ophthalmology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042597
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1042597
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)