Is Lipid Profile Associated with Bone Mineral Density and Bone Formation in Subjects with Spinal Cord Injury?

المؤلفون المشاركون

Sabour, Hadis
Norouzi Javidan, Abbas
Latifi, Sahar
Hadian, Mohammad Reza
Emami Razavi, Seyed-Hassan
Shidfar, Farzad
Vafa, Mohammad Reza
Aghaei Meybodi, Hamidreza

المصدر

Journal of Osteoporosis

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-08-21

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Purpose.

The association between serum lipids and bone mineral density (BMD) has been investigated previously but, up to now, these relationships have not yet been described in spinal cord injury (SCI).

We tried to assess the correlation between serum triglyceride (TG), total cholesterol (TC), high-density lipoprotein (HDL), and low-density lipoprotein (LDL) and BMD in male subjects with SCI.

Methods.

Dual-energy X-ray absorptiometry (DXA) was used to assess BMD in femoral neck, trochanter, intertrochanteric zone, and lumbar vertebras.

Blood samples were taken to measure serums lipids and bone biomarkers including osteocalcin, cross-linked type I collagen (CTX), and bone alkaline phosphatase (BALP).

Partial correlation analysis was used to evaluate the relationships between mentioned measurements after adjustment for weight and age.

Results.

We found a positive correlation between HDL and femoral neck BMD ( P : 0.004, r = 0.33 ).

HDL was negatively correlated with osteocalcin ( P : 0.017, r = - 0.31 ) which was not in consistency with its relationship with BMD.

TC and LDL were not related to CTX, BALP and BMD.

Conclusion.

This study does not support a strong association between serum lipids and BMD in subjects with SCI.

Moreover it seems that positive association between HDL and BMD is not mediated through increased bone formation.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sabour, Hadis& Norouzi Javidan, Abbas& Latifi, Sahar& Hadian, Mohammad Reza& Emami Razavi, Seyed-Hassan& Shidfar, Farzad…[et al.]. 2014. Is Lipid Profile Associated with Bone Mineral Density and Bone Formation in Subjects with Spinal Cord Injury?. Journal of Osteoporosis،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042704

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sabour, Hadis…[et al.]. Is Lipid Profile Associated with Bone Mineral Density and Bone Formation in Subjects with Spinal Cord Injury?. Journal of Osteoporosis No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1042704

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sabour, Hadis& Norouzi Javidan, Abbas& Latifi, Sahar& Hadian, Mohammad Reza& Emami Razavi, Seyed-Hassan& Shidfar, Farzad…[et al.]. Is Lipid Profile Associated with Bone Mineral Density and Bone Formation in Subjects with Spinal Cord Injury?. Journal of Osteoporosis. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1042704

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1042704