Stress-Induced Mast Cell Activation in Glabrous and Hairy Skin
المؤلفون المشاركون
Căruntu, Constantin
Boda, Daniel
Musat, Sorin
Căruntu, Ana
Mandache, Eugen
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Mast cells play a key role in modulation of stress-induced cutaneous inflammation.
In this study we investigate the impact of repeated exposure to stress on mast cell degranulation, in both hairy and glabrous skin.
Adult male Wistar rats were randomly divided into four groups: Stress 1 day ( n = 8 ) , Stress 10 days ( n = 7 ) , Stress 21 days ( n = 6 ) , and Control ( n = 8 ) .
Rats in the stress groups were subjected to 2 h/day restraint stress.
Subsequently, glabrous and hairy skin samples from animals of all groups were collected to assess mast cell degranulation by histochemistry and transmission electron microscopy.
The impact of stress on mast cell degranulation was different depending on the type of skin and duration of stress exposure.
Short-term stress exposure induced an amplification of mast cell degranulation in hairy skin that was maintained after prolonged exposure to stress.
In glabrous skin, even though acute stress exposure had a profound stimulating effect on mast cell degranulation, it diminished progressively with long-term exposure to stress.
The results of our study reinforce the view that mast cells are active players in modulating skin responses to stress and contribute to further understanding of pathophysiological mechanisms involved in stress-induced initiation or exacerbation of cutaneous inflammatory processes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Căruntu, Constantin& Boda, Daniel& Musat, Sorin& Căruntu, Ana& Mandache, Eugen. 2014. Stress-Induced Mast Cell Activation in Glabrous and Hairy Skin. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1043310
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Căruntu, Constantin…[et al.]. Stress-Induced Mast Cell Activation in Glabrous and Hairy Skin. Mediators of Inflammation No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-1043310
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Căruntu, Constantin& Boda, Daniel& Musat, Sorin& Căruntu, Ana& Mandache, Eugen. Stress-Induced Mast Cell Activation in Glabrous and Hairy Skin. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-1043310
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043310
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر