Subnormal Peripheral Blood Leukocyte Counts Are Related to the Lowest Prevalence and Incidence of Metabolic Syndrome: Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study

المؤلفون المشاركون

Sun, Shaomei
Wu, Hongmei
Zhang, Qing
Wang, Chongjin
Guo, Yinting
Du, Huanmin
Liu, Li
Jia, Qiyu
Wang, Xing
Song, Kun
Niu, Kaijun

المصدر

Mediators of Inflammation

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-04-29

دولة النشر

مصر

عدد الصفحات

12

التخصصات الرئيسية

الأمراض

الملخص EN

Few studies have assessed the relationship between a subnormal inflammatory status and metabolic syndrome (MS).

We therefore designed a cross-sectional and 5-year cohort study to evaluate how a subnormal peripheral blood leukocyte count is related to MS.

Participants were recruited from Tianjin Medical University General Hospital-Health Management Centre.

Both a baseline cross-sectional (n=46,179) and a prospective assessment (n=13,061) were performed.

Participants without a history of MS were followed up for 5 years.

Leukocyte counts and MS components were assessed at baseline and yearly during the follow-up.

Adjusted logistic and Cox proportional hazards regression models were used to assess relationships between the categories of leukocyte counts and MS.

The subnormal leukocyte counts group (1,100–3,900 cells/mm3) had the lowest prevalence and incidence of MS.

The odds ratio and hazard ratio (95% confidence interval) of the highest leukocyte counts were 1.98 (1.57–2.49) and 1.50 (1.22–1.84) (both P for trend <0.0001), respectively, when compared to the subnormal leukocyte counts group after adjusting for potential confounders.

This study has shown that subnormal leukocyte counts are independently related to the lowest prevalence and incidence of MS.

The findings suggest that it is necessary to restudy and discuss the clinical or preventive value of subnormal leukocyte counts.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sun, Shaomei& Wu, Hongmei& Zhang, Qing& Wang, Chongjin& Guo, Yinting& Du, Huanmin…[et al.]. 2014. Subnormal Peripheral Blood Leukocyte Counts Are Related to the Lowest Prevalence and Incidence of Metabolic Syndrome: Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1043544

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sun, Shaomei…[et al.]. Subnormal Peripheral Blood Leukocyte Counts Are Related to the Lowest Prevalence and Incidence of Metabolic Syndrome: Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study. Mediators of Inflammation No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1043544

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sun, Shaomei& Wu, Hongmei& Zhang, Qing& Wang, Chongjin& Guo, Yinting& Du, Huanmin…[et al.]. Subnormal Peripheral Blood Leukocyte Counts Are Related to the Lowest Prevalence and Incidence of Metabolic Syndrome: Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1043544

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1043544