The Effects of Florfenicol on the Values of Serum Tumor Necrosis Factor- α and Other Biochemical Markers in Lipopolysaccharide-Induced Endotoxemia in Brown Trout
المؤلفون المشاركون
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-29
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The aim of the present study was to determine the effects of florfenicol on the expected changes in sTNF-α, damage markers of the liver and kidney, and the lipid metabolism parameters in endotoxemic brown trout.
Ninety-six brown trout were included in this study.
After six of the fish were reserved as the control group, the remaining 90 fish were divided equally into 3 groups as follows: LPS (2 mg/kg, IP), LPS (2 mg/kg, IP) + florfenicol (40 mg/kg, IM), and florfenicol (40 mg/kg, IM).
Blood samples were obtained from the tail of the fish at 1.5, 3, 6, 10, and 24 hours.
The levels of sTNF-α were determined by ELISA and biochemical markers were evaluated with an autoanalyzer.
A significant increase was observed in the values of sTNF-α in the LPS and LPS + florfenicol groups ( P < 0.05 ).
Significant increases were found in the kidney and liver damage determinants in the LPS and LPS + florfenicol groups ( P < 0.05 ).
Irregular changes in the lipid metabolism parameters were observed in all the subgroups.
In conclusion, florfenicol does not affect the increases of sTNF-α caused by LPS and does not prevent liver or kidney damage; at least, it can be said that florfenicol does not have any evident positive effects on the acute endotoxemia of fish.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Er, Ayse& Dik, Burak. 2014. The Effects of Florfenicol on the Values of Serum Tumor Necrosis Factor- α and Other Biochemical Markers in Lipopolysaccharide-Induced Endotoxemia in Brown Trout. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1043571
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Er, Ayse& Dik, Burak. The Effects of Florfenicol on the Values of Serum Tumor Necrosis Factor- α and Other Biochemical Markers in Lipopolysaccharide-Induced Endotoxemia in Brown Trout. Mediators of Inflammation No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1043571
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Er, Ayse& Dik, Burak. The Effects of Florfenicol on the Values of Serum Tumor Necrosis Factor- α and Other Biochemical Markers in Lipopolysaccharide-Induced Endotoxemia in Brown Trout. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1043571
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043571
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر