![](/images/graphics-bg.png)
Abnormal Cytokine Profile in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Erectile Dysfunction
المؤلفون المشاركون
Siafakas, Nikolaos M.
Bouloukaki, Izolde
Papadimitriou, Vaios
Sofras, Frank
Mermigkis, Charalampos
Moniaki, Violeta
Schiza, Sophia E.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-19
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) show a high prevalence of erectile dysfunction (ED).
Although the underlying pathogenesis is still unknown, endothelial dysfunction, induced by inflammatory cytokines, chemokines, and adhesion molecules, has been proposed as a possible mechanism.
The aim of this study was to assess whether OSAHS is associated with activation of the inflammatory cytokine system in patients with ED compared to the matched OSAHS patients with normal sexual function.
Thirty-one patients with severe OSAHS and ED were included.
Fifteen patients with severe OSAHS and without ED served as controls.
Serum concentrations of high-sensitivity C-reactive protein (hsCRP), tumor necrosis factor-α (TNF-a), interleukin-6 (IL-6), interleukin-8 (IL-8), and adiponectin were measured after the diagnostic polysomnography.
We found that hsCRP levels were significantly elevated in OSAHS patients with ED compared to controls.
Similarly, TNF-a levels, IL-6, and IL-8 were elevated in OSAHS patients with ED compared to controls.
Serum adiponectin levels were lower in OSAHS-ED patients, but the difference did not reach statistical significance.
The presence of ED in patients with severe OSAHS is associated with elevated levels of inflammatory markers, underlining a possible involvement of endothelial dysfunction in the pathogenesis of ED.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bouloukaki, Izolde& Papadimitriou, Vaios& Sofras, Frank& Mermigkis, Charalampos& Moniaki, Violeta& Siafakas, Nikolaos M.…[et al.]. 2014. Abnormal Cytokine Profile in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Erectile Dysfunction. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043645
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bouloukaki, Izolde…[et al.]. Abnormal Cytokine Profile in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Erectile Dysfunction. Mediators of Inflammation No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1043645
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bouloukaki, Izolde& Papadimitriou, Vaios& Sofras, Frank& Mermigkis, Charalampos& Moniaki, Violeta& Siafakas, Nikolaos M.…[et al.]. Abnormal Cytokine Profile in Patients with Obstructive Sleep Apnea-Hypopnea Syndrome and Erectile Dysfunction. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1043645
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043645
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)