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Association between Parathyroid Hormone Levels and Inflammatory Markers among US Adults
المؤلفون المشاركون
Cheng, Shih-Ping
Liu, Chien-Liang
Liu, Tsang-Pai
Hsu, Yi-Chiung
Lee, Jie-Jen
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background and Aims.
High levels of parathyroid hormone (PTH) appear to be associated with an increased mortality.
Previous studies concerning the relationship of inflammatory markers with hyperparathyroidism have yielded inconsistent results.
This study investigated whether serum PTH concentrations were independently associated with several inflammatory markers among the US adults.
Materials and Methods.
Using data from the National Health and Nutrition Examination Survey, we examined the relation between serum PTH and C-reactive protein (CRP), red cell distribution width (RDW), and platelet-to-lymphocyte ratio (PLR) levels with weighted linear regression.
Additionally, we examined the relation with increased modified Glasgow Prognostic Score (mGPS) by using weighted logistic regression.
Results.
CRP, RDW, and PLR values increased with increasing serum PTH concentration.
After extensively adjusting for covariates, CRP and RDW increased linearly and across PTH categories (all P < 0.001 ), while PLR marginally increased ( P = 0.190 and P = 0.095 using PTH as a categorical and continuous variable, resp.).
The odds ratio of increased mGPS was 1.11 and 1.31 across PTH categories and with increasing PTH levels continuously.
Conclusion.
These nationally representative data indicate that serum PTH levels are independently associated with several inflammatory markers in the US population.
The casual relationship between PTH levels and inflammation remains to be elucidated.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cheng, Shih-Ping& Liu, Chien-Liang& Liu, Tsang-Pai& Hsu, Yi-Chiung& Lee, Jie-Jen. 2014. Association between Parathyroid Hormone Levels and Inflammatory Markers among US Adults. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1043747
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cheng, Shih-Ping…[et al.]. Association between Parathyroid Hormone Levels and Inflammatory Markers among US Adults. Mediators of Inflammation No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1043747
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cheng, Shih-Ping& Liu, Chien-Liang& Liu, Tsang-Pai& Hsu, Yi-Chiung& Lee, Jie-Jen. Association between Parathyroid Hormone Levels and Inflammatory Markers among US Adults. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1043747
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043747
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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