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Change in Growth Differentiation Factor 15, but Not C-Reactive Protein, Independently Predicts Major Cardiac Events in Patients with Non-ST Elevation Acute Coronary Syndrome
المؤلفون المشاركون
Dominguez-Rodriguez, Alberto
Abreu-Gonzalez, Pedro
Hernandez-Baldomero, Idaira F.
Bosa-Ojeda, Francisco
Avanzas, Pablo
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-15
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Among the numerous emerging biomarkers, high-sensitivity C-reactive protein (hsCRP) and growth-differentiation factor-15 (GDF-15) have received widespread interest, with their potential role as predictors of cardiovascular risk.
The concentrations of inflammatory biomarkers, however, are influenced, among others, by physiological variations, which are the natural, within-individual variation occurring over time.
The aims of our study are: (a) to describe the changes in hsCRP and GDF-15 levels over a period of time and after an episode of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) and (b) to examine whether the rate of change in hsCRP and GDF-15 after the acute event is associated with long-term major cardiovascular adverse events (MACE).
Two hundred and Fifty five NSTE-ACS patients were included in the study.
We measured hsCRP and GDF-15 concentrations, at admission and again 36 months after admission (end of the follow-up period).
The present study shows that the change of hsCRP levels, measured after 36 months, does not predict MACE in NSTEACS-patients.
However, the level of GDF-15 measured, after 36 months, was a stronger predictor of MACE, in comparison to the acute unstable phase.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dominguez-Rodriguez, Alberto& Abreu-Gonzalez, Pedro& Hernandez-Baldomero, Idaira F.& Avanzas, Pablo& Bosa-Ojeda, Francisco. 2014. Change in Growth Differentiation Factor 15, but Not C-Reactive Protein, Independently Predicts Major Cardiac Events in Patients with Non-ST Elevation Acute Coronary Syndrome. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1043902
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dominguez-Rodriguez, Alberto…[et al.]. Change in Growth Differentiation Factor 15, but Not C-Reactive Protein, Independently Predicts Major Cardiac Events in Patients with Non-ST Elevation Acute Coronary Syndrome. Mediators of Inflammation No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1043902
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dominguez-Rodriguez, Alberto& Abreu-Gonzalez, Pedro& Hernandez-Baldomero, Idaira F.& Avanzas, Pablo& Bosa-Ojeda, Francisco. Change in Growth Differentiation Factor 15, but Not C-Reactive Protein, Independently Predicts Major Cardiac Events in Patients with Non-ST Elevation Acute Coronary Syndrome. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1043902
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043902
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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