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Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring
المؤلفون المشاركون
Almeida Morais, Carina
Oyama, Lila Missae
Oliveira, Juliana Lopez de
Carvalho Garcia, Márcia
Rosso, Veridiana Vera de
Sousa Mendes Amigo, Laís
Pisani, Luciana Pellegrini
Oller do Nascimento, Claudia Maria da Penha
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-07
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Maternal intake of trans-fatty acids (TFAs) in the perinatal period triggers a proinflammatory state in offspring.
Anthocyanins contained in fruit are promising modulators of inflammation.
This study investigated the effect of Jussara supplementation in the maternal diet on the proinflammatory state of the colon in offspring exposed to perinatal TFAs.
On the first day of pregnancy rats were divided into four groups: control diet (C), control diet with 0.5% Jussara supplementation (CJ), diet enriched with hydrogenated vegetable fat, rich in TFAs (T), or T diet supplemented with 0.5% Jussara (TJ) during pregnancy and lactation.
We showed that Jussara supplementation in maternal diet (CJ and TJ groups) reduced carcass lipid/protein ratios, serum lipids, glucose, IL-6, TNF-α, gene expression of IL-6R, TNF-αR (P<0.05), TLR-4 (P<0.01), and increase Lactobacillus spp.
(P<0.05) in the colon of offspring compared to the T group.
The IL-10 (P=0.035) and IL-10/TNF-α ratio (P<0.01) was higher in the CJ group than in the T group.
The 0.5% Jussara supplementation reverses the adverse effects of perinatal TFAs, improving lipid profiles, glucose levels, body composition, and gut microbiota and reducing low-grade inflammation in the colon of 21-day-old offspring, and could contribute to reducing chronic disease development.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Almeida Morais, Carina& Oyama, Lila Missae& Oliveira, Juliana Lopez de& Carvalho Garcia, Márcia& Rosso, Veridiana Vera de& Sousa Mendes Amigo, Laís…[et al.]. 2014. Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043967
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Almeida Morais, Carina…[et al.]. Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring. Mediators of Inflammation No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1043967
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Almeida Morais, Carina& Oyama, Lila Missae& Oliveira, Juliana Lopez de& Carvalho Garcia, Márcia& Rosso, Veridiana Vera de& Sousa Mendes Amigo, Laís…[et al.]. Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043967
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1043967
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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