Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring
Joint Authors
Almeida Morais, Carina
Oyama, Lila Missae
Oliveira, Juliana Lopez de
Carvalho Garcia, Márcia
Rosso, Veridiana Vera de
Sousa Mendes Amigo, Laís
Pisani, Luciana Pellegrini
Oller do Nascimento, Claudia Maria da Penha
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-09-07
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Maternal intake of trans-fatty acids (TFAs) in the perinatal period triggers a proinflammatory state in offspring.
Anthocyanins contained in fruit are promising modulators of inflammation.
This study investigated the effect of Jussara supplementation in the maternal diet on the proinflammatory state of the colon in offspring exposed to perinatal TFAs.
On the first day of pregnancy rats were divided into four groups: control diet (C), control diet with 0.5% Jussara supplementation (CJ), diet enriched with hydrogenated vegetable fat, rich in TFAs (T), or T diet supplemented with 0.5% Jussara (TJ) during pregnancy and lactation.
We showed that Jussara supplementation in maternal diet (CJ and TJ groups) reduced carcass lipid/protein ratios, serum lipids, glucose, IL-6, TNF-α, gene expression of IL-6R, TNF-αR (P<0.05), TLR-4 (P<0.01), and increase Lactobacillus spp.
(P<0.05) in the colon of offspring compared to the T group.
The IL-10 (P=0.035) and IL-10/TNF-α ratio (P<0.01) was higher in the CJ group than in the T group.
The 0.5% Jussara supplementation reverses the adverse effects of perinatal TFAs, improving lipid profiles, glucose levels, body composition, and gut microbiota and reducing low-grade inflammation in the colon of 21-day-old offspring, and could contribute to reducing chronic disease development.
American Psychological Association (APA)
Almeida Morais, Carina& Oyama, Lila Missae& Oliveira, Juliana Lopez de& Carvalho Garcia, Márcia& Rosso, Veridiana Vera de& Sousa Mendes Amigo, Laís…[et al.]. 2014. Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring. Mediators of Inflammation،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043967
Modern Language Association (MLA)
Almeida Morais, Carina…[et al.]. Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring. Mediators of Inflammation No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1043967
American Medical Association (AMA)
Almeida Morais, Carina& Oyama, Lila Missae& Oliveira, Juliana Lopez de& Carvalho Garcia, Márcia& Rosso, Veridiana Vera de& Sousa Mendes Amigo, Laís…[et al.]. Jussara (Euterpe edulis Mart.) Supplementation during Pregnancy and Lactation Modulates the Gene and Protein Expression of Inflammation Biomarkers Induced by trans-Fatty Acids in the Colon of Offspring. Mediators of Inflammation. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1043967
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1043967