Symptoms and Association with Health Outcomes in Relapsing-Remitting Multiple Sclerosis: Results of a US Patient Survey
المؤلفون المشاركون
Vietri, Jeffrey
Williams, Angela E.
Isherwood, Gina
Flor, Armando
المصدر
Multiple Sclerosis International
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-09-23
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
A variety of symptoms have been reported, but the prevalence of specific symptoms in relapsing-remitting multiple sclerosis (RRMS), how they are related to one another, and their impact on patient reported outcomes is not well understood.
Objective.
To describe how symptoms of RRMS cooccur and their impact on patient-reported outcomes.
Methods.
Individuals who reported a physician diagnosis of RRMS in a large general health survey in the United States indicated the symptoms they experience because of RRMS and completed validated scales, including the work productivity and activity impairment questionnaire and either the SF-12v2 or SF-36v2.
Symptom clusters were identified through hierarchical cluster analysis, and the relationship between clusters and outcomes was assessed through regression.
Results.
Fatigue, difficulty walking, and numbness were the most commonly reported symptoms.
Seven symptom clusters were identified, and several were significantly related to patient reported outcomes.
Pain, muscle spasms, and stiffness formed a cluster strongly related to physical quality of life; depression was strongly related to mental quality of life and cognitive difficulty was associated with work impairment.
Conclusions.
Symptoms in RRMS show a strong relationship with quality of life and should be taken into consideration in treatment decisions and evaluation of treatment success.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Williams, Angela E.& Vietri, Jeffrey& Isherwood, Gina& Flor, Armando. 2014. Symptoms and Association with Health Outcomes in Relapsing-Remitting Multiple Sclerosis: Results of a US Patient Survey. Multiple Sclerosis International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1046594
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Williams, Angela E.…[et al.]. Symptoms and Association with Health Outcomes in Relapsing-Remitting Multiple Sclerosis: Results of a US Patient Survey. Multiple Sclerosis International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1046594
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Williams, Angela E.& Vietri, Jeffrey& Isherwood, Gina& Flor, Armando. Symptoms and Association with Health Outcomes in Relapsing-Remitting Multiple Sclerosis: Results of a US Patient Survey. Multiple Sclerosis International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1046594
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1046594
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر