Is Walking Capacity in Subjects with Multiple Sclerosis Primarily Related to Muscle Oxidative Capacity or Maximal Muscle Strength? A Pilot Study
المؤلفون المشاركون
Hansen, Dominique
Wens, Inez
Eijnde, Bert O.
Feys, Peter
المصدر
Multiple Sclerosis International
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-01-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background and Purpose.
Walking capacity is reduced in subjects with multiple sclerosis (MS).
To develop effective exercise interventions to enhance walking capacity, it is important to determine the impact of factors, modifiable by exercise intervention (maximal muscle strength versus muscle oxidative capacity), on walking capacity.
The purpose of this pilot study is to discriminate between the impact of maximal muscle strength versus muscle oxidative capacity on walking capacity in subjects with MS.
Methods.
From 24 patients with MS, muscle oxidative capacity was determined by calculation of exercise-onset oxygen uptake kinetics (mean response time) during submaximal exercise bouts.
Maximal muscle strength (isometric knee extension and flexion peak torque) was assessed on dynamometer.
All subjects completed a 6-minute walking test.
Relationships between walking capacity (as a percentage of normal value) and muscle strength (of knee flexors and extensors) versus muscle oxidative capacity were assessed in multivariate regression analyses.
Results.
The expanded disability status score (EDSS) showed a significant univariate correlation ( r = - 0.70 , P < 0.004 ) with walking capacity.
In multivariate regression analyses, EDSS and mean response time, but not muscle strength, were independently related to walking capacity ( P < 0.05 ).
Conclusions.
Walking distance is, next to disability level and not taking neurologic symptoms/deficits into account, primarily related to muscle oxidative capacity in subjects with MS.
Additional study is needed to further examine/verify these findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hansen, Dominique& Feys, Peter& Wens, Inez& Eijnde, Bert O.. 2014. Is Walking Capacity in Subjects with Multiple Sclerosis Primarily Related to Muscle Oxidative Capacity or Maximal Muscle Strength? A Pilot Study. Multiple Sclerosis International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1046613
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hansen, Dominique…[et al.]. Is Walking Capacity in Subjects with Multiple Sclerosis Primarily Related to Muscle Oxidative Capacity or Maximal Muscle Strength? A Pilot Study. Multiple Sclerosis International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-1046613
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hansen, Dominique& Feys, Peter& Wens, Inez& Eijnde, Bert O.. Is Walking Capacity in Subjects with Multiple Sclerosis Primarily Related to Muscle Oxidative Capacity or Maximal Muscle Strength? A Pilot Study. Multiple Sclerosis International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1046613
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1046613
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر