Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study

المؤلفون المشاركون

Horvathova, Martina
Orszaghova, Zuzana
Laubertova, Lucia
Vavakova, Magdalena
Sabaka, Peter
Rohdewald, Peter
Durackova, Zdenka
Muchova, Jana

المصدر

Oxidative Medicine and Cellular Longevity

العدد

المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2014-08-31

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الأحياء

الملخص EN

We examined in vitro antioxidant capacity of polyphenolic extract obtained from the wood of oak Quercus robur (QR), Robuvit, using TEAC (Trolox equivalent antioxidant capacity) method and the effect of its intake on markers of oxidative stress, activity of antioxidant enzymes, and total antioxidant capacity in plasma of 20 healthy volunteers.

Markers of oxidative damage to proteins, DNA, and lipids and activities of Cu/Zn-superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were determined in the erythrocytes.

We have found an in vitro antioxidant capacity of Robuvit of 6.37 micromole Trolox equivalent/mg of Robuvit.

One month intake of Robuvit in daily dose of 300 mg has significantly decreased the serum level of advanced oxidation protein products (AOPP) and lipid peroxides (LP).

Significantly increased activities of SOD and CAT as well as total antioxidant capacity of plasma after one month intake of Robuvit have been shown.

In conclusion, we have demonstrated for the first time that the intake of Robuvit is associated with decrease of markers of oxidative stress and increase of activity of antioxidant enzymes and total antioxidant capacity of plasma in vivo.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Horvathova, Martina& Orszaghova, Zuzana& Laubertova, Lucia& Vavakova, Magdalena& Sabaka, Peter& Rohdewald, Peter…[et al.]. 2014. Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047073

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Horvathova, Martina…[et al.]. Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047073

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Horvathova, Martina& Orszaghova, Zuzana& Laubertova, Lucia& Vavakova, Magdalena& Sabaka, Peter& Rohdewald, Peter…[et al.]. Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047073

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1047073