Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study
Joint Authors
Horvathova, Martina
Orszaghova, Zuzana
Laubertova, Lucia
Vavakova, Magdalena
Sabaka, Peter
Rohdewald, Peter
Durackova, Zdenka
Muchova, Jana
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We examined in vitro antioxidant capacity of polyphenolic extract obtained from the wood of oak Quercus robur (QR), Robuvit, using TEAC (Trolox equivalent antioxidant capacity) method and the effect of its intake on markers of oxidative stress, activity of antioxidant enzymes, and total antioxidant capacity in plasma of 20 healthy volunteers.
Markers of oxidative damage to proteins, DNA, and lipids and activities of Cu/Zn-superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were determined in the erythrocytes.
We have found an in vitro antioxidant capacity of Robuvit of 6.37 micromole Trolox equivalent/mg of Robuvit.
One month intake of Robuvit in daily dose of 300 mg has significantly decreased the serum level of advanced oxidation protein products (AOPP) and lipid peroxides (LP).
Significantly increased activities of SOD and CAT as well as total antioxidant capacity of plasma after one month intake of Robuvit have been shown.
In conclusion, we have demonstrated for the first time that the intake of Robuvit is associated with decrease of markers of oxidative stress and increase of activity of antioxidant enzymes and total antioxidant capacity of plasma in vivo.
American Psychological Association (APA)
Horvathova, Martina& Orszaghova, Zuzana& Laubertova, Lucia& Vavakova, Magdalena& Sabaka, Peter& Rohdewald, Peter…[et al.]. 2014. Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047073
Modern Language Association (MLA)
Horvathova, Martina…[et al.]. Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-6.
https://search.emarefa.net/detail/BIM-1047073
American Medical Association (AMA)
Horvathova, Martina& Orszaghova, Zuzana& Laubertova, Lucia& Vavakova, Magdalena& Sabaka, Peter& Rohdewald, Peter…[et al.]. Effect of the French Oak Wood Extract Robuvit on Markers of Oxidative Stress and Activity of Antioxidant Enzymes in Healthy Volunteers: A Pilot Study. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-1047073
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047073