Role of Lipid Peroxidation Products, Plasma Total Antioxidant Status, and Cu-, Zn-Superoxide Dismutase Activity as Biomarkers of Oxidative Stress in Elderly Prediabetics
المؤلفون المشاركون
Kokot, Teresa
Dzięgielewska-Gęsiak, Sylwia
Wysocka, Ewa
Michalak, Sławomir
Nowakowska-Zajdel, Ewa
Muc-Wierzgoń, Małgorzata
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-05
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The relationship between hyperglycemia and oxidative stress in diabetes is well known, but the influence of metabolic disturbances recognized as prediabetes, in elderly patients especially, awaits for an explanation.
Methods.
52 elderly persons (65 years old and older) with no acute or severe chronic disorders were assessed: waist circumference (WC), body mass index (BMI), percentage of body fat (FAT), and arterial blood pressure.
During an oral glucose tolerance test (OGTT) fasting (0′) and 120-minute (120′) glycemia and insulinemia were determined, and type 2 diabetics (n=6) were excluded.
Subjects were tested for glycated hemoglobin HbA1c, plasma lipids, total antioxidant status (TAS), thiobarbituric acid-reacting substances (TBARS), and activity of erythrocyte superoxide dismutase (SOD-1).
According to OGTT results, patients were classified as normoglycemics, (NGT, n=18) and prediabetics, (PRE, n=28).
Results.
Both groups did not differ with their lipids, FAT, and TBARS.
PRE group had higher WC (P<0.002) and BMI (P<0.002).
Lower SOD-1 activity (P<0.04) and TAS status (P<0.04) were found in PRE versus NGT group.
Significance.
In elderly prediabetics, SOD-1 and TAS seem to reflect the first symptoms of oxidative stress, while TBARS are later biomarkers of oxidative stress.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dzięgielewska-Gęsiak, Sylwia& Wysocka, Ewa& Michalak, Sławomir& Nowakowska-Zajdel, Ewa& Kokot, Teresa& Muc-Wierzgoń, Małgorzata. 2014. Role of Lipid Peroxidation Products, Plasma Total Antioxidant Status, and Cu-, Zn-Superoxide Dismutase Activity as Biomarkers of Oxidative Stress in Elderly Prediabetics. Oxidative Medicine and Cellular Longevity،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047176
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dzięgielewska-Gęsiak, Sylwia…[et al.]. Role of Lipid Peroxidation Products, Plasma Total Antioxidant Status, and Cu-, Zn-Superoxide Dismutase Activity as Biomarkers of Oxidative Stress in Elderly Prediabetics. Oxidative Medicine and Cellular Longevity No. 2014 (Dec. 2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1047176
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dzięgielewska-Gęsiak, Sylwia& Wysocka, Ewa& Michalak, Sławomir& Nowakowska-Zajdel, Ewa& Kokot, Teresa& Muc-Wierzgoń, Małgorzata. Role of Lipid Peroxidation Products, Plasma Total Antioxidant Status, and Cu-, Zn-Superoxide Dismutase Activity as Biomarkers of Oxidative Stress in Elderly Prediabetics. Oxidative Medicine and Cellular Longevity. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1047176
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1047176
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر