Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network
المؤلفون المشاركون
Hackshaw, Michelle D.
Chen, Clara
Borker, Rohit
Ewing, James
Tseng, Wan-Yu
Saravanan, Shanmugapriya
Dhanda, Rahul
Nadler, Eric
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Purpose.
To assess epidemiology, treatment patterns, and outcomes of metastatic soft tissue sarcoma (mSTS) patients in USA community oncology practices.
Methods.
This retrospective, descriptive study used US Oncology’s iKnowMed electronic health records database.
Adults (≥18 years) with mSTS and at least two visits between July 2007 and June 2010 were included.
Key outcomes were practice patterns, overall survival (OS), and progression-free survival (PFS).
Results.
363 mSTS patients (174 treated and 189 untreated) met the prespecified exclusion/inclusion criteria.
The most common subtypes were leiomyosarcoma (n=104; 29%), liposarcoma (n=40; 11%), and synovial sarcoma (n=12; 3%); the remainder (n=207; 57%) comprised 27 histologic subtypes.
Treated patients were younger and had lower ECOG scores; 75% and 25% received first-line combination or monotherapy, respectively.
Median OS of treated and untreated patients was 22 and 17 months, respectively, and 29 months in patients with the three most common subtypes.
Before controlling for effects of covariates, younger age and lower ECOG scores were associated with better OS and PFS.
Conclusion.
This study provides insights into mSTS epidemiology, treatment patterns, and outcomes in a large community-based oncology network.
These results warrant further studies with larger cohorts.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Clara& Borker, Rohit& Ewing, James& Tseng, Wan-Yu& Hackshaw, Michelle D.& Saravanan, Shanmugapriya…[et al.]. 2013. Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network. Complexity،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047440
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Clara…[et al.]. Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network. Complexity Vol. 2014, no. 2014 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1047440
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Clara& Borker, Rohit& Ewing, James& Tseng, Wan-Yu& Hackshaw, Michelle D.& Saravanan, Shanmugapriya…[et al.]. Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network. Complexity. 2013. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047440
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1047440
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر