Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network
Joint Authors
Hackshaw, Michelle D.
Chen, Clara
Borker, Rohit
Ewing, James
Tseng, Wan-Yu
Saravanan, Shanmugapriya
Dhanda, Rahul
Nadler, Eric
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
To assess epidemiology, treatment patterns, and outcomes of metastatic soft tissue sarcoma (mSTS) patients in USA community oncology practices.
Methods.
This retrospective, descriptive study used US Oncology’s iKnowMed electronic health records database.
Adults (≥18 years) with mSTS and at least two visits between July 2007 and June 2010 were included.
Key outcomes were practice patterns, overall survival (OS), and progression-free survival (PFS).
Results.
363 mSTS patients (174 treated and 189 untreated) met the prespecified exclusion/inclusion criteria.
The most common subtypes were leiomyosarcoma (n=104; 29%), liposarcoma (n=40; 11%), and synovial sarcoma (n=12; 3%); the remainder (n=207; 57%) comprised 27 histologic subtypes.
Treated patients were younger and had lower ECOG scores; 75% and 25% received first-line combination or monotherapy, respectively.
Median OS of treated and untreated patients was 22 and 17 months, respectively, and 29 months in patients with the three most common subtypes.
Before controlling for effects of covariates, younger age and lower ECOG scores were associated with better OS and PFS.
Conclusion.
This study provides insights into mSTS epidemiology, treatment patterns, and outcomes in a large community-based oncology network.
These results warrant further studies with larger cohorts.
American Psychological Association (APA)
Chen, Clara& Borker, Rohit& Ewing, James& Tseng, Wan-Yu& Hackshaw, Michelle D.& Saravanan, Shanmugapriya…[et al.]. 2013. Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network. Complexity،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047440
Modern Language Association (MLA)
Chen, Clara…[et al.]. Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network. Complexity Vol. 2014, no. 2014 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-1047440
American Medical Association (AMA)
Chen, Clara& Borker, Rohit& Ewing, James& Tseng, Wan-Yu& Hackshaw, Michelle D.& Saravanan, Shanmugapriya…[et al.]. Epidemiology, Treatment Patterns, and Outcomes of Metastatic Soft Tissue Sarcoma in a Community-Based Oncology Network. Complexity. 2013. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-1047440
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1047440