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Determination of Residual Nonsteroidal Anti-Inflammatory Drugs in Aqueous Sample Using Magnetic Nanoparticles Modified with Cetyltrimethylammonium Bromide by High Performance Liquid Chromatography
المؤلفون المشاركون
Waqif-Husain, S.
Mehdinia, Ali
Khoeini Sharifabadi, Malihe
Saber Tehrani, Mohammad
Aberoomand Azar, Parviz
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
A simple and sensitive solid-phase extraction method for separation and preconcentration of trace amount of four nonsteroidal anti-inflammatory drugs (naproxen, indomethacin, diclofenac, and ibuprofen) using Fe3O4 magnetic nanoparticles modified with cetyltrimethylammonium bromide has been developed.
For this purpose, the surface of MNP s was modified with cetyltrimethylammonium bromide (CTAB) as a cationic surfactant.
Effects of different parameters influencing the extraction efficiency of drugs including the pH, amount of salt, shaking time, eluent type, the volume of solvent, amount of adsorbent, sample volume, and the time of desorption were investigated and optimized.
Methanol has been used as desorption solvent and the extracts were analysed on a reversed-phase octadecyl silica column using 0.02 M phosphate-buffer (pH = 6.02) acetonitrile (65 : 35 v/v) as the mobile phase and the effluents were measured at 202 nm with ultraviolet detector.
The relative standard deviation (RSD%) of the method was investigated at three concentrations (25, 50, and 200 ng/mL) and was in the range of 3.98–9.83% ( n = 6 ) for 50 ng/mL.
The calibration curves obtained for studied drugs show reasonable linearity ( R 2 > 0.99 ) and the limit of detection (LOD s ) ranged between 2 and 7 ng/mL.
Finally, the proposed method has been effectively employed in extraction and determination of the drugs in biological and environmental samples.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Khoeini Sharifabadi, Malihe& Saber Tehrani, Mohammad& Waqif-Husain, S.& Mehdinia, Ali& Aberoomand Azar, Parviz. 2014. Determination of Residual Nonsteroidal Anti-Inflammatory Drugs in Aqueous Sample Using Magnetic Nanoparticles Modified with Cetyltrimethylammonium Bromide by High Performance Liquid Chromatography. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1048387
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Khoeini Sharifabadi, Malihe…[et al.]. Determination of Residual Nonsteroidal Anti-Inflammatory Drugs in Aqueous Sample Using Magnetic Nanoparticles Modified with Cetyltrimethylammonium Bromide by High Performance Liquid Chromatography. The Scientific World Journal No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-1048387
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Khoeini Sharifabadi, Malihe& Saber Tehrani, Mohammad& Waqif-Husain, S.& Mehdinia, Ali& Aberoomand Azar, Parviz. Determination of Residual Nonsteroidal Anti-Inflammatory Drugs in Aqueous Sample Using Magnetic Nanoparticles Modified with Cetyltrimethylammonium Bromide by High Performance Liquid Chromatography. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-1048387
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1048387
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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