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Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells
المؤلفون المشاركون
Palomba, S.
Orio, Francesco
Muscogiuri, Giovanna
Serio, Bianca
Sessa, Mariarosaria
Giudice, Valentina
Ferrara, Idalucia
Tauchmanovà, Libuse
Colao, Annamaria
Selleri, Carmine
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-30
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Early and late endocrine disorders are among the most common complications in survivors after hematopoietic allogeneic- (allo-) and autologous- (auto-) stem cell transplant (HSCT).
This review summarizes main endocrine disorders reported in literature and observed in our center as consequence of auto- and allo-HSCT and outlines current options for their management.
Gonadal impairment has been found early in approximately two-thirds of auto- and allo-HSCT patients: 90–99% of women and 60–90% of men.
Dysfunctions of the hypothalamus-pituitary-growth hormone/insulin growth factor-I axis, hypothalamus-pituitary-thyroid axis, and hypothalamus-pituitary-adrenal axis were documented as later complicances, occurring in about 10, 30, and 40–50% of transplanted patients, respectively.
Moreover, overt or subclinical thyroid complications (including persistent low-T3 syndrome, chronic thyroiditis, subclinical hypo- or hyperthyroidism, and thyroid carcinoma), gonadal failure, and adrenal insufficiency may persist many years after HSCT.
Our analysis further provides evidence that main recognized risk factors for endocrine complications after HSCT are the underlying disease, previous pretransplant therapies, the age at HSCT, gender, total body irradiation, posttransplant derangement of immune system, and in the allogeneic setting, the presence of graft-versus-host disease requiring prolonged steroid treatment.
Early identification of endocrine complications can greatly improve the quality of life of long-term survivors after HSCT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Orio, Francesco& Muscogiuri, Giovanna& Palomba, S.& Serio, Bianca& Sessa, Mariarosaria& Giudice, Valentina…[et al.]. 2014. Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1049060
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Orio, Francesco…[et al.]. Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells. The Scientific World Journal No. 2014 (2014), pp.1-13.
https://search.emarefa.net/detail/BIM-1049060
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Orio, Francesco& Muscogiuri, Giovanna& Palomba, S.& Serio, Bianca& Sessa, Mariarosaria& Giudice, Valentina…[et al.]. Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-13.
https://search.emarefa.net/detail/BIM-1049060
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1049060
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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