Clinical Factors Associated with Sperm DNA Fragmentation in Male Patients with Infertility
المؤلفون المشاركون
Komiya, A.
Kawauchi, Yoko
Kato, Tomonori
Watanabe, Akihiko
Fuse, Hideki
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-03
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Objective.
The clinical factors associated with sperm DNA fragmentation (SDF) were investigated in male patients with infertility.
Materials and Methods.
Fifty-four ejaculates from infertile Japanese males were used.
Thirty-three and twenty-one were from the patients with varicoceles and idiopathic causes of infertility, respectively.
We performed blood tests, including the serum sex hormone levels, and conventional and computer-assisted semen analyses.
The sperm nuclear vacuolization (SNV) was evaluated using a high-magnification microscope.
The SDF was evaluated using the sperm chromatin dispersion test (SCDt) to determine the SDF index (SDFI).
The SDFI was compared with semen parameters and other clinical variables, including lifestyle factors.
Results.
The SDFI was 41.3 ± 22.2% (mean ± standard deviation) and did not depend on the cause of infertility.
Chronic alcohol use increased the SDFI to 49.6 ± 23.3% compared with 33.9 ± 18.0% in nondrinkers.
The SDFI was related to adverse conventional semen parameters and sperm motion characteristics and correlated with the serum FSH level.
The SNV showed a tendency to increase with the SDFI.
The multivariate analysis revealed that the sperm progressive motility and chronic alcohol use were significant predictors of the SDF.
Conclusion.
The SCDt should be offered to chronic alcohol users and those with decreased sperm progressive motility.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Komiya, A.& Kato, Tomonori& Kawauchi, Yoko& Watanabe, Akihiko& Fuse, Hideki. 2014. Clinical Factors Associated with Sperm DNA Fragmentation in Male Patients with Infertility. The Scientific World Journal،Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1051412
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Komiya, A.…[et al.]. Clinical Factors Associated with Sperm DNA Fragmentation in Male Patients with Infertility. The Scientific World Journal No. 2014 (2014), pp.1-11.
https://search.emarefa.net/detail/BIM-1051412
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Komiya, A.& Kato, Tomonori& Kawauchi, Yoko& Watanabe, Akihiko& Fuse, Hideki. Clinical Factors Associated with Sperm DNA Fragmentation in Male Patients with Infertility. The Scientific World Journal. 2014. Vol. 2014, no. 2014, pp.1-11.
https://search.emarefa.net/detail/BIM-1051412
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1051412
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر