Morphological Changes in the Bone Marrow of the Dogs with Visceral Leishmaniasis
المؤلفون المشاركون
Momo, Claudia
Jacintho, Ana Paula Prudente
Moreira, Pamela Rodrigues Reina
Munari, Danísio Prado
Machado, Gisele Fabrino
Vasconcelos, Rosemeri de Oliveira
المصدر
Veterinary Medicine International
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-05
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The aim of this study was to evaluate the most frequent lesions in the bone marrow of dogs naturally infected by Leishmania (Leishmania) chagasi.
Thirty-three dogs sacrificed at the Zoonosis Control Center of Araçatuba, a municipality endemic for visceral leishmaniasis (VL), were used.
The animals were classified as asymptomatic, oligosymptomatic, and symptomatic groups.
At the necropsy, bone marrow samples were collected from the femur, fixed, processed, and stained with hematoxylin and eosin.
The lesion intensity was classified as mild, moderate, or severe.
The parasite load was determined using immunohistochemistry.
The most important lesions consisted of multifocal to diffuse granulomas, megakaryocytic dysplasia, and medullary aplasia.
There were no statistical differences between the three clinical groups regarding parasite load and lesion intensity.
Asymptomatic dogs also presented high parasitism in the bone marrow as dogs with clinical signs of VL.
It was concluded that, regardless of clinical group, the bone marrow is a site for multiplication of Leishmania chagasi.
Possibly, the bone marrow dysplasia may arise from the presence of many parasitized and activated macrophages in this organ.
Consequently, it affects the profile of hematopoietic cells in the bone marrow and systemic circulation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Momo, Claudia& Jacintho, Ana Paula Prudente& Moreira, Pamela Rodrigues Reina& Munari, Danísio Prado& Machado, Gisele Fabrino& Vasconcelos, Rosemeri de Oliveira. 2014. Morphological Changes in the Bone Marrow of the Dogs with Visceral Leishmaniasis. Veterinary Medicine International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1051890
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Momo, Claudia…[et al.]. Morphological Changes in the Bone Marrow of the Dogs with Visceral Leishmaniasis. Veterinary Medicine International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-1051890
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Momo, Claudia& Jacintho, Ana Paula Prudente& Moreira, Pamela Rodrigues Reina& Munari, Danísio Prado& Machado, Gisele Fabrino& Vasconcelos, Rosemeri de Oliveira. Morphological Changes in the Bone Marrow of the Dogs with Visceral Leishmaniasis. Veterinary Medicine International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-1051890
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1051890
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر