Effects of Acute Bleeding Followed by Hydroxyethyl Starch 1300.4 or a Crystalloid on Propofol Concentrations, Cerebral Oxygenation, and Electroencephalographic and Haemodynamic Variables in Pigs
المؤلفون المشاركون
Silva, Aura
Ortiz, Ana Liza
Venâncio, Carlos
Souza, Almir P.
Ferreira, Luísa Maria
Branco, Paula Sério
de Pinho, Paula Guedes
Amorim, Pedro
Ferreira, David A.
المصدر
Veterinary Medicine International
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-19
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Bleeding changes the haemodynamics, compromising organ perfusion.
In this study, the effects of bleeding followed by replacement with hydroxyethyl starch 130/0.4 (HES) or lactated Ringer’s (LR) on cerebral oxygenation and electroencephalogram-derived parameters were investigated.
Twelve young pigs under propofol-remifentanil anaesthesia were bled 30 mL/kg and, after a 20-minute waiting period, volume replacement was performed with HES (GHES; N = 6 ) or LR (GRL; N = 6 ).
Bleeding caused a decrease of more than 50% in mean arterial pressure ( P < 0.01 ) and a decrease in cerebral oximetry ( P = 0.039 ), bispectral index, and electroencephalogram total power ( P = 0.04 and P < 0.01 , resp.), while propofol plasma concentrations increased ( P < 0.01 ).
Both solutions restored the haemodynamics and cerebral oxygenation similarly and were accompanied by an increase in electroencephalogram total power.
No differences between groups were found.
However, one hour after the end of the volume replacement, the cardiac output ( P = 0.03 ) and the cerebral oxygenation ( P = 0.008 ) decreased in the GLR and were significantly lower than in GHES ( P = 0.02 ).
Volume replacement with HES 130/0.4 was capable of maintaining the cardiac output and cerebral oxygenation during a longer period than LR and caused a decrease in the propofol plasma concentrations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Silva, Aura& Ortiz, Ana Liza& Venâncio, Carlos& Souza, Almir P.& Ferreira, Luísa Maria& Branco, Paula Sério…[et al.]. 2014. Effects of Acute Bleeding Followed by Hydroxyethyl Starch 1300.4 or a Crystalloid on Propofol Concentrations, Cerebral Oxygenation, and Electroencephalographic and Haemodynamic Variables in Pigs. Veterinary Medicine International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1051940
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Silva, Aura…[et al.]. Effects of Acute Bleeding Followed by Hydroxyethyl Starch 1300.4 or a Crystalloid on Propofol Concentrations, Cerebral Oxygenation, and Electroencephalographic and Haemodynamic Variables in Pigs. Veterinary Medicine International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-1051940
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Silva, Aura& Ortiz, Ana Liza& Venâncio, Carlos& Souza, Almir P.& Ferreira, Luísa Maria& Branco, Paula Sério…[et al.]. Effects of Acute Bleeding Followed by Hydroxyethyl Starch 1300.4 or a Crystalloid on Propofol Concentrations, Cerebral Oxygenation, and Electroencephalographic and Haemodynamic Variables in Pigs. Veterinary Medicine International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-1051940
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1051940
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر