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Comparison of Histochemical Stainings in Evaluation of Liver Fibrosis and Correlation with Transient Elastography in Chronic Hepatitis
المؤلفون المشاركون
Maida, Marcello
Cabibi, Daniela
Bronte, Fabrizio
Porcasi, Rossana
Ingrao, Sabrina
Giannone, Antonino Giulio
Grazia Bavetta, Maria
Petta, Salvatore
Di Marco, Vito
Calvaruso, Vincenza
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-11-17
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background and Aim.
The best staining to evaluate liver fibrosis in liver hepatitis is still a debated topic.
This study aimed to compare Masson’s trichrome (MT), Sirius Red (SR), and orcein stainings in evaluating liver fibrosis in chronic HCV hepatitis (CHC) with semiquantitative and quantitative methods (Collagen Proportionate Area (CPA) by Digital Image Analysis (DIA)) and correlate them with transient elastography (TE).
Methods.
Liver stiffness evaluation of 111 consecutive patients with CHC was performed by TE.
Semiquantitative staging by Metavir score system and CPA by DIA were assessed on liver biopsy stained with MT, SR, and orcein.
Results.
MT, SR, and orcein staining showed concordant results in 89.6% of cases in staging CHC, without significant difference in both semiquantitative and quantitative evaluations of fibrosis.
TE values were concordant with orcein levels in 86.5% of the cases and with MT/RS in 77.5% ( P < 0.001 ).
No significant correlation between the grade of necroinflammatory activity and TE values was found.
Conclusion.
In CHC, SR/MT and orcein stainings are almost concordant and when discordant, orcein staining is better related to TE values than MT/RS.
This suggests that elastic fibers play a more important role than reticular or collagenous ones in determining stiffness values in CHC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cabibi, Daniela& Bronte, Fabrizio& Porcasi, Rossana& Ingrao, Sabrina& Giannone, Antonino Giulio& Maida, Marcello…[et al.]. 2015. Comparison of Histochemical Stainings in Evaluation of Liver Fibrosis and Correlation with Transient Elastography in Chronic Hepatitis. Analytical Cellular Pathology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1052355
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cabibi, Daniela…[et al.]. Comparison of Histochemical Stainings in Evaluation of Liver Fibrosis and Correlation with Transient Elastography in Chronic Hepatitis. Analytical Cellular Pathology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1052355
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cabibi, Daniela& Bronte, Fabrizio& Porcasi, Rossana& Ingrao, Sabrina& Giannone, Antonino Giulio& Maida, Marcello…[et al.]. Comparison of Histochemical Stainings in Evaluation of Liver Fibrosis and Correlation with Transient Elastography in Chronic Hepatitis. Analytical Cellular Pathology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1052355
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1052355
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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