Frequency of Red Cell Alloimmunization and Autoimmunization in Thalassemia Patients: A Report from Eastern India
المؤلفون المشاركون
Bhattacharya, Prasun
Datta, Suvro Sankha
Mukherjee, Somnath
Talukder, Biplabendu
Mukherjee, Krishnendu
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-06
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Red blood cell (RBC) alloimmunization and autoimmunization remain a major problem in transfusion dependent thalassemic patients.
There is a paucity of data on the incidence of RBC alloimmunization and autoimmunization in thalassemic patients from eastern part of India, as pretransfusion antibody screening is not routinely performed.
Aims.
To assess the incidence of RBC alloimmunization and autoimmunization in transfusion dependent thalassemic patients in eastern India.
Materials and Methods.
Total 500 thalassemia cases were evaluated.
The antibody screening and identification were performed with commercially available panel cells (Diapanel, Bio-rad, Switzerland) by column agglutination method.
To detect autoantibodies, autocontrol and direct antiglobulin tests were carried out using polyspecific coombs (IgG + C3d) gel cards in all patients.
Results.
A total of 28 patients developed RBC alloimmunization (5.6%) and 5 patients had autoantibodies (1%).
Alloantibody against c had the highest incidence (28.57%) followed by E (21.42%).
Five out of 28 (17.85%) patients had developed antibodies against both c and E.
Conclusion.
Data from this study demonstrate that the RBC alloantibody and autoantibody development rates are significant in our region.
Thus, pretransfusion antibody screening needs to be initiated in eastern India in order to ensure safe transfusion practice.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Datta, Suvro Sankha& Mukherjee, Somnath& Talukder, Biplabendu& Bhattacharya, Prasun& Mukherjee, Krishnendu. 2015. Frequency of Red Cell Alloimmunization and Autoimmunization in Thalassemia Patients: A Report from Eastern India. Advances in Hematology،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1052444
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Datta, Suvro Sankha…[et al.]. Frequency of Red Cell Alloimmunization and Autoimmunization in Thalassemia Patients: A Report from Eastern India. Advances in Hematology No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1052444
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Datta, Suvro Sankha& Mukherjee, Somnath& Talukder, Biplabendu& Bhattacharya, Prasun& Mukherjee, Krishnendu. Frequency of Red Cell Alloimmunization and Autoimmunization in Thalassemia Patients: A Report from Eastern India. Advances in Hematology. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1052444
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1052444
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر