Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice
المؤلفون المشاركون
Schaefer, Roland
Virgin, Garth
Geisel, Tabea
Stein, Jürgen
Bach, Matthias
Martin, Julia
Schulze, Bettina
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-07-05
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Current iron supplementation practice in geriatric patients is erratic and lacks evidence-based recommendations.
Despite potential benefits in this population, intravenous iron supplementation is often withheld due to concerns regarding pharmacy expense, perceived safety issues, and doubts regarding efficacy in elderly patients.
This retrospective, observational cohort study aimed to evaluate the safety and efficacy of intravenous ferric carboxymaltose (FCM, Ferinject) in patients aged >75 years with iron deficiency anaemia (IDA).
Within a twelve-month data extraction period, the charts of 405 hospitalised patients aged 65–101 years were retrospectively analysed for IDA, defined according to WHO criteria for anaemia (haemoglobin: <13.0 g/dL (m)/<12.0 g/dL (f)) in conjunction with transferrin saturation <20%.
Of 128 IDA patients screened, 51 (39.8%) received intravenous iron.
38 patient charts were analysed.
Mean cumulative dose of intravenous FCM was 784.4 ± 271.7 mg iron (1–3 infusions).
18 patients (47%) fulfilled treatment response criteria (≥1.0 g/dL increase in haemoglobin between baseline and hospital discharge).
AEs were mild/moderate, most commonly transient increases of liver enzymes (n = 5/13.2%).
AE incidence was comparable with that observed in patients <75 years.
No serious AEs were observed.
Ferric carboxymaltose was well tolerated and effective for correction of Hb levels and iron stores in this cohort of IDA patients aged over 75 years.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bach, Matthias& Geisel, Tabea& Martin, Julia& Schulze, Bettina& Schaefer, Roland& Virgin, Garth…[et al.]. 2015. Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice. Anemia،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1053782
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bach, Matthias…[et al.]. Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice. Anemia No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1053782
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bach, Matthias& Geisel, Tabea& Martin, Julia& Schulze, Bettina& Schaefer, Roland& Virgin, Garth…[et al.]. Efficacy and Safety of Intravenous Ferric Carboxymaltose in Geriatric Inpatients at a German Tertiary University Teaching Hospital: A Retrospective Observational Cohort Study of Clinical Practice. Anemia. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1053782
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1053782
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر