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Enzyme Inhibitory Properties, Antioxidant Activities, and Phytochemical Profile of Three Medicinal Plants from Turkey
المؤلفون المشاركون
Picot, Carene M. N.
Mahmudi, M. Fawzi
Zengin, Gokhan
Guler, Gokalp Ozmen
Aktumsek, Abdurrahman
Ceylan, Ramazan
المصدر
Advances in Pharmacological and Pharmaceutical Sciences
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
We aimed to investigate the inhibitory potential of three medicinal plants (Hedysarum varium, Onobrychis hypargyrea, and Vicia truncatula) from Turkey against key enzymes involved in human pathologies, namely, diabetes (α-amylase and α-glucosidase), neurodegenerative disorders (tyrosinase, acetylcholinesterase, and butyrylcholinesterase), and hyperpigmentation (tyrosinase).
The antioxidant potential, phenolic and flavonoid content of ethyl acetate, and methanolic and aqueous extracts were investigated using in vitro assays.
The total antioxidant capacity (TAC), β-carotene/linoleic acid bleaching activity, 1,1-diphenyl-2-picrylhydrazyl free radical (DPPH•), 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS•+), cupric ion reducing antioxidant capacity (CUPRAC), ferric reducing antioxidant power (FRAP), and metal chelating activity on ferrous ions were used to evaluate the antioxidant capabilities of the extracts.
The half-maximal inhibitory concentrations (IC50) of the extracts on cholinesterase, tyrosinase, and α-amylase were significantly higher than the references, galantamine, kojic acid, and acarbose, respectively.
The half-maximal effective concentrations (EC50) of the extracts on TAC, CUPRAC, and FRAP were significantly higher than trolox.
The phenol and flavonoid contents of the plant extracts were in the range 20.90 ± 0.190 – 83.25 ± 0.914 mg gallic acid equivalent/g extract and 1.45 ± 0.200 – 39.71 ± 0.092 mg rutin equivalent/g extract, respectively.
The plants were found to possess moderate antioxidant capacities and interesting inhibitory action against key enzymes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zengin, Gokhan& Guler, Gokalp Ozmen& Aktumsek, Abdurrahman& Ceylan, Ramazan& Picot, Carene M. N.& Mahmudi, M. Fawzi. 2015. Enzyme Inhibitory Properties, Antioxidant Activities, and Phytochemical Profile of Three Medicinal Plants from Turkey. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1053904
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zengin, Gokhan…[et al.]. Enzyme Inhibitory Properties, Antioxidant Activities, and Phytochemical Profile of Three Medicinal Plants from Turkey. Advances in Pharmacological and Pharmaceutical Sciences No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1053904
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zengin, Gokhan& Guler, Gokalp Ozmen& Aktumsek, Abdurrahman& Ceylan, Ramazan& Picot, Carene M. N.& Mahmudi, M. Fawzi. Enzyme Inhibitory Properties, Antioxidant Activities, and Phytochemical Profile of Three Medicinal Plants from Turkey. Advances in Pharmacological and Pharmaceutical Sciences. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1053904
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1053904
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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