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Salvage Pelvic Lymph Node Dissection in Recurrent Prostate Cancer: Surgical and Early Oncological Outcome
المؤلفون المشاركون
Claeys, Tom
Van Praet, Charles
Fonteyne, Valérie
Lambert, Bieke
Delrue, Louke
De Visschere, Pieter
Villeirs, Geert
Decaestecker, Karel
Ost, Piet
De Meerleer, Gert
Lumen, Nicolaas
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Methodology.
Seventeen patients with prostate-specific antigen (PSA) rise following local treatment for prostate cancer with curative intent underwent open or minimally invasive salvage pelvic lymph node dissection (SLND) for oligometastatic disease (<4 synchronous metastases) or as staging prior to salvage radiotherapy.
Biochemical recurrence after complete biochemical response (cBR) was defined as 2 consecutive PSA increases >0,2 ng/mL; and after incomplete biochemical response as 2 consecutive PSA rises.
Newly found metastasis on imaging defined clinical progression (CP).
Palliative androgen deprivation therapy (ADT) was initiated if >3 metastases were detected or if patients became symptomatic.
Kaplan-Meier statistics were applied.
Results.
Clavien-Dindo grade 1, 2, 3a, and 3b complications were seen in 6, 1, 1, and 2 patients, respectively.
Median follow-up time was 22 months.
Among 13 patients treated for oligometastatic disease, 8 (67%) had a PSA decline, with 3 patients showing cBR.
Median PSA progression-free survival (FS) was 4.1 months and median CP-FS 7 months.
Three patients started ADT, resulting in a 2-year ADT-FS rate of 79.5%.
Conclusion.
SLND is feasible, but postoperative complication rate seems higher than that for primary LND.
Biochemical and clinical response duration is limited, but as part of an oligometastatic treatment regime it can defer palliative ADT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Claeys, Tom& Van Praet, Charles& Lumen, Nicolaas& Ost, Piet& Fonteyne, Valérie& De Meerleer, Gert…[et al.]. 2015. Salvage Pelvic Lymph Node Dissection in Recurrent Prostate Cancer: Surgical and Early Oncological Outcome. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054606
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Claeys, Tom…[et al.]. Salvage Pelvic Lymph Node Dissection in Recurrent Prostate Cancer: Surgical and Early Oncological Outcome. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054606
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Claeys, Tom& Van Praet, Charles& Lumen, Nicolaas& Ost, Piet& Fonteyne, Valérie& De Meerleer, Gert…[et al.]. Salvage Pelvic Lymph Node Dissection in Recurrent Prostate Cancer: Surgical and Early Oncological Outcome. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054606
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054606
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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