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Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature
المؤلفون المشاركون
Di Nicola, Maura
Barteselli, Giulio
Dell’Arti, Laura
Ratiglia, Roberto
Viola, Francesco
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-06-08
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Deferoxamine mesylate (DFO) is the most commonly used iron-chelating agent to treat transfusion-related hemosiderosis.
Despite the clear advantages for the use of DFO, numerous DFO-related systemic toxicities have been reported in the literature, as well as sight-threatening ocular toxicity involving the retinal pigment epithelium (RPE).
The damage to the RPE can lead to visual field defects, color-vision defects, abnormal electrophysiological tests, and permanent visual deterioration.
The purpose of this review is to provide an updated summary of the ocular findings, including both functional and structural abnormalities, in DFO-treated patients.
In particular, we pay particular attention to analyzing results of multimodal technologies for retinal imaging, which help ophthalmologists in the early diagnosis and correct management of DFO retinopathy.
Fundus autofluorescence, for example, is not only useful for screening patients at high-risk of DFO retinopathy, but is also a prerequisite for identify specific high-risk patterns of RPE changes that are relevant for the prognosis of the disease.
In addition, optical coherence tomography may have a clinical usefulness in detecting extent and location of different retinal changes in DFO retinopathy.
Finally, this review wants to underline the need for universally approved guidelines for screening and followup of this particular disease.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Di Nicola, Maura& Barteselli, Giulio& Dell’Arti, Laura& Ratiglia, Roberto& Viola, Francesco. 2015. Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature. BioMed Research International،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054751
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Di Nicola, Maura…[et al.]. Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature. BioMed Research International No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1054751
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Di Nicola, Maura& Barteselli, Giulio& Dell’Arti, Laura& Ratiglia, Roberto& Viola, Francesco. Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1054751
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054751
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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