Endothelial Injury Associated with Cold or Warm Blood Cardioplegia during Coronary Artery Bypass Graft Surgery
المؤلفون المشاركون
Kuhn, Elmar W.
Choi, Yeong-Hoon
Pyun, Jung-Min
Neef, Klaus
Liakopoulos, Oliver J.
Stamm, Christof
Wittwer, Thorsten
Wahlers, Thorsten
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The aim of this investigation was to analyze the impact of intermittent cold blood cardioplegia (ICC) and intermittent warm blood cardioplegia (IWC) on endothelial injury in patients referred to elective on-pump coronary artery bypass graft (CABG) surgery.
Patients undergoing CABG procedures were randomized to either ICC or IWC.
Myocardial injury was assessed by CK-MB and cardiac troponin T (cTnT).
Endothelial injury was quantified by circulating endothelial cells (CECs), von Willebrand factor (vWF), and soluble thrombomodulin (sTM).
Perioperative myocardial injury (PMI) and major adverse cardiac events (MACE) were recorded.
Demographic data and preoperative risk profile of included patients (ICC: n=32, IWC: n=36) were comparable.
No deaths, PMI, or MACE were observed.
Levels of CK-MB and cTnT did not show intergroup differences.
Concentrations of CECs peaked at 6 h postoperatively with significantly higher values for IWC-patients at 1 h (ICC: 10.1 ± 3.9/mL; IWC: 18.4 ± 4.1/mL; P=0.012) and 6 h (ICC: 19.3 ± 6.2/mL; IWC: 29.2 ± 6.7/mL; P<0.001).
Concentrations of vWF (ICC: 178.4 ± 73.2 U/dL; IWC: 258.2 ± 89.7 U/dL; P<0.001) and sTM (ICC: 3.2 ± 2.1 ng/mL; IWC: 5.2 ± 2.4 ng/mL; P=0.011) were significantly elevated in IWC-group at 1 h postoperatively.
This study shows that the use of IWC is associated with a higher extent of endothelial injury compared to ICC without differences in clinical endpoints.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kuhn, Elmar W.& Choi, Yeong-Hoon& Pyun, Jung-Min& Neef, Klaus& Liakopoulos, Oliver J.& Stamm, Christof…[et al.]. 2015. Endothelial Injury Associated with Cold or Warm Blood Cardioplegia during Coronary Artery Bypass Graft Surgery. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054774
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kuhn, Elmar W.…[et al.]. Endothelial Injury Associated with Cold or Warm Blood Cardioplegia during Coronary Artery Bypass Graft Surgery. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1054774
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kuhn, Elmar W.& Choi, Yeong-Hoon& Pyun, Jung-Min& Neef, Klaus& Liakopoulos, Oliver J.& Stamm, Christof…[et al.]. Endothelial Injury Associated with Cold or Warm Blood Cardioplegia during Coronary Artery Bypass Graft Surgery. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1054774
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054774
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر