Neuronal Nitric Oxide Synthase Is Dislocated in Type I Fibers of Myalgic Muscle but Can Recover with Physical Exercise Training
المؤلفون المشاركون
Sjøgaard, Gisela
Jensen, L.
Andersen, L. L.
Schrøder, H. D.
Frandsen, U.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-17
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Trapezius myalgia is the most common type of chronic neck pain.
While physical exercise reduces pain and improves muscle function, the underlying mechanisms remain unclear.
Nitric oxide (NO) signaling is important in modulating cellular function, and a dysfunctional neuronal NO synthase (nNOS) may contribute to an ineffective muscle function.
This study investigated nNOS expression and localization in chronically painful muscle.
Forty-one women clinically diagnosed with trapezius myalgia (MYA) and 18 healthy controls (CON) were included in the case-control study.
Subsequently, MYA were randomly assigned to either 10 weeks of specific strength training (SST, n = 18 ), general fitness training (GFT, n = 15 ), or health information (REF, n = 8 ).
Distribution of fiber type, cross-sectional area, and sarcolemmal nNOS expression did not differ between MYA and CON.
However, MYA showed increased sarcoplasmic nNOS localization (18.8 ± 12 versus 12.8 ± 8%, P = 0.049 ) compared with CON.
SST resulted in a decrease of sarcoplasm-localized nNOS following training (before 18.1 ± 12 versus after 12.0 ± 12%; P = 0 ,027).
We demonstrate that myalgic muscle displays altered nNOS localization and that 10 weeks of strength training normalize these disruptions, which supports previous findings of impaired muscle oxygenation during work tasks and reduced pain following exercise.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jensen, L.& Andersen, L. L.& Schrøder, H. D.& Frandsen, U.& Sjøgaard, Gisela. 2015. Neuronal Nitric Oxide Synthase Is Dislocated in Type I Fibers of Myalgic Muscle but Can Recover with Physical Exercise Training. BioMed Research International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1054816
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jensen, L.…[et al.]. Neuronal Nitric Oxide Synthase Is Dislocated in Type I Fibers of Myalgic Muscle but Can Recover with Physical Exercise Training. BioMed Research International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1054816
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jensen, L.& Andersen, L. L.& Schrøder, H. D.& Frandsen, U.& Sjøgaard, Gisela. Neuronal Nitric Oxide Synthase Is Dislocated in Type I Fibers of Myalgic Muscle but Can Recover with Physical Exercise Training. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1054816
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1054816
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر