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Clinical Significance of Neutrophil Gelatinase-Associated Lipocalin in Crimean-Congo Hemorrhagic Fever
المؤلفون المشاركون
Cure, Erkan
Yuce, Suleyman
Erturk, Ayse
Parlak, Emine
Sahin, Serap Baydur
Cumhur Cure, Medine
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-22
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Neutrophil gelatinase-associated lipocalin (NGAL), which is an important prognostic marker for sepsis and inflammatory diseases, is mostly released from neutrophils.
Crimean-Congo hemorrhagic fever (CCHF) patients are generally neutropenic.
We aimed to investigate whether there is a change in serum NGAL level and to investigate its effect on the recovery time (RT) during the course of CCHF.
A total of 40 CCHF patients (19 females and 21 males) and 34 healthy controls (17 females and 17 males) were included in the study.
The serum NGAL level and biochemical and hematological parameters were checked.
The NGAL level of CCHF patients was significantly higher than that of the healthy controls ( P < 0.001 ).
A multivariate analysis showed that the independent prognostic factor for the prediction of the RT is the NGAL level (odds ratio [OR] 0.3, 95% confidence interval [Cl] 0.1–0.4, P < 0.001 ).
An elevated NGAL level was found to be associated with an increased RT in CCHF patients.
The NGAL levels of CHHF patients might be elevated due to increased cytokine release, the presence of a tissue injury, and the release of immature neutrophils from the bone marrow into the peripheral stream.
This may be a good prognostic factor in CHHF patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Erturk, Ayse& Cure, Erkan& Parlak, Emine& Cumhur Cure, Medine& Sahin, Serap Baydur& Yuce, Suleyman. 2015. Clinical Significance of Neutrophil Gelatinase-Associated Lipocalin in Crimean-Congo Hemorrhagic Fever. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055234
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Erturk, Ayse…[et al.]. Clinical Significance of Neutrophil Gelatinase-Associated Lipocalin in Crimean-Congo Hemorrhagic Fever. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1055234
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Erturk, Ayse& Cure, Erkan& Parlak, Emine& Cumhur Cure, Medine& Sahin, Serap Baydur& Yuce, Suleyman. Clinical Significance of Neutrophil Gelatinase-Associated Lipocalin in Crimean-Congo Hemorrhagic Fever. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1055234
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055234
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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