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The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats
المؤلفون المشاركون
El Rabey, Haddad A.
al-Malki, Abdulrahman L.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-05
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The antidiabetic activity of two low doses of Moringa seed powder (50 and 100 mg/kg body weight, in the diet) on streptozotocin (STZ) induced diabetes male rats was investigated.
Forty rats were divided into four groups.
The diabetic positive control (STZ treated) group showed increased lipid peroxide, increased IL-6, and decreased antioxidant enzyme in the serum and kidney tissue homogenate compared with that of the negative control group.
Immunoglobulins (IgA, IgG), fasting blood sugar, and glycosylated hemoglobin ( H b A 1 c ) were also increased as a result of diabetes in G2 rats.
Moreover albumin was decreased, and liver enzymes and α-amylase were not affected.
In addition, the renal functions and potassium and sodium levels in G2 were increased as a sign of diabetic nephropathy.
Urine analysis showed also glucosuria and increased potassium, sodium, creatinine, uric acid, and albumin levels.
Kidney and pancreas tissues showed also pathological alteration compared to the negative control group.
Treating the diabetic rats with 50 or 100 mg Moringa seeds powder/kg body weight in G3 and G4, respectively, ameliorated the levels of all these parameters approaching the negative control values and restored the normal histology of both kidney and pancreas compared with that of the diabetic positive control group.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
al-Malki, Abdulrahman L.& El Rabey, Haddad A.. 2015. The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats. BioMed Research International،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1055255
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
al-Malki, Abdulrahman L.& El Rabey, Haddad A.. The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats. BioMed Research International No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1055255
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
al-Malki, Abdulrahman L.& El Rabey, Haddad A.. The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1055255
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055255
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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