Effect of Left Ventricular Outflow Tract Obstruction on Left Atrial Mechanics in Hypertrophic Cardiomyopathy
المؤلفون المشاركون
Williams, Lynne K.
Chan, Raymond H.
Carasso, Shemy
Durand, Miranda
Misurka, Jimmy
Ralph-Edwards, Anthony
Gruner, Christiane
Woo, Anna
Lesser, John R.
Maron, Barry J.
Maron, Martin S.
Rakowski, Harry
Crean, Andrew M.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-16
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Left atrial (LA) volumes are known to be increased in hypertrophic cardiomyopathy (HCM) and are a predictor of adverse outcome.
In addition, LA function is impaired and is presumed to be due to left ventricular (LV) diastolic dysfunction as a result of hypertrophy and myocardial fibrosis.
In the current study, we assess the incremental effect of outflow tract obstruction (and concomitant mitral regurgitation) on LA function as assessed by LA strain.
Patients with HCM (50 obstructive, 50 nonobstructive) were compared to 50 normal controls.
A subset of obstructive patients who had undergone septal myectomy was also studied.
Utilising feature-tracking software applied to cardiovascular magnetic resonance images, LA volumes and functional parameters were calculated.
LA volumes were significantly elevated and LA ejection fraction and strain were significantly reduced in patients with HCM compared with controls and were significantly more affected in patients with obstruction.
LA volumes and function were significantly improved after septal myectomy.
LVOT obstruction and mitral regurgitation appear to further impair LA mechanics.
Septal myectomy results in a significant reduction in LA volumes, paralleled by an improvement in function.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Williams, Lynne K.& Chan, Raymond H.& Carasso, Shemy& Durand, Miranda& Misurka, Jimmy& Crean, Andrew M.…[et al.]. 2015. Effect of Left Ventricular Outflow Tract Obstruction on Left Atrial Mechanics in Hypertrophic Cardiomyopathy. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055637
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Williams, Lynne K.…[et al.]. Effect of Left Ventricular Outflow Tract Obstruction on Left Atrial Mechanics in Hypertrophic Cardiomyopathy. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1055637
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Williams, Lynne K.& Chan, Raymond H.& Carasso, Shemy& Durand, Miranda& Misurka, Jimmy& Crean, Andrew M.…[et al.]. Effect of Left Ventricular Outflow Tract Obstruction on Left Atrial Mechanics in Hypertrophic Cardiomyopathy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1055637
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055637
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر