Identification of Type II Interferon Receptors in Geese: Gene Structure, Phylogenetic Analysis, and Expression Patterns
المؤلفون المشاركون
Chen, Shun
Qi, Yulin
Wang, Mingshu
Zhu, Dekang
Liu, Mafeng
Chen, Xiaoyue
Cheng, Anchun
Zhou, Hao
Zhou, Qin
Jia, Renyong
Liu, Fei
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-08-06
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Interferon γ receptor 1 (IFNGR1) and IFNGR2 are two cell membrane molecules belonging to class II cytokines, which play important roles in the IFN-mediated antiviral signaling pathway.
Here, goose IFNGR1 and IFNGR2 were cloned and identified for the first time.
Tissue distribution analysis revealed that relatively high levels of goose IFNγ mRNA transcripts were detected in immune tissues, including the harderian gland, cecal tonsil, cecum, and thymus.
Relatively high expression levels of both IFNGR1 and IFNGR2 were detected in the cecal tonsil, which implicated an important role of IFNγ in the secondary immune system of geese.
No specific correlation between IFNγ, IFNGR1, and IFNGR2 expression levels was observed in the same tissues of healthy geese.
IFNγ and its cognate receptors showed different expression profiles, although they appeared to maintain a relatively balanced state.
Furthermore, the agonist R848 led to the upregulation of goose IFNγ but did not affect the expression of goose IFNGR1 or IFNGR2.
In summary, trends in expression of goose IFNγ and its cognate receptors showed tissue specificity, as well as an age-related dependency.
These findings may help us to better understand the age-related susceptibility to pathogens in birds.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhou, Hao& Chen, Shun& Qi, Yulin& Zhou, Qin& Wang, Mingshu& Jia, Renyong…[et al.]. 2015. Identification of Type II Interferon Receptors in Geese: Gene Structure, Phylogenetic Analysis, and Expression Patterns. BioMed Research International،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1055868
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhou, Hao…[et al.]. Identification of Type II Interferon Receptors in Geese: Gene Structure, Phylogenetic Analysis, and Expression Patterns. BioMed Research International No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1055868
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhou, Hao& Chen, Shun& Qi, Yulin& Zhou, Qin& Wang, Mingshu& Jia, Renyong…[et al.]. Identification of Type II Interferon Receptors in Geese: Gene Structure, Phylogenetic Analysis, and Expression Patterns. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1055868
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055868
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر