Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA1c with Time
المؤلفون المشاركون
Lee, Byung-Wan
Cha, Bong Soo
Lee, Hyun Chul
Kim, Kwang Joon
Yoon, Hye-jin
Kim, So Ra
Kang, Eun Seok
Lee, Yong-ho
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-09-21
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
We recently reported that glycated albumin (GA) is increased in subjects with longer duration of diabetes and with decreased insulin secretory function.
Based on this, we investigated whether GA increases with time relative to glycated hemoglobin (HbA1c) and the association between GA and beta-cell function.
We analyzed 340 type 2 diabetes patients whose serum GA and HbA1c levels had been repeatedly measured over 4 years.
We assessed the pattern of changes with time in glycemic indices (GA, HbA1c, and GA/HbA1c ratio) and their relationship with beta-cell function.
In all patients, glycemic indices decreased and maintained low levels around 15 and 27 months.
However, from 39 months to 51 months, GA significantly increased but HbA1c tended to increase without statistical significance.
We defined ΔGA/HbA1c as the difference between the nadir point (at 15 to 27 months) and the end point (at 39 to 51 months) and found that ΔGA/HbA1c was positively correlated with diabetes duration and negatively related to beta-cell function.
In multivariable linear regression analyses, ΔGA/HbA1c was independently associated with diabetes duration.
In conclusion, this study demonstrated that serum GA levels increase relative to HbA1c levels with time.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yoon, Hye-jin& Lee, Yong-ho& Kim, Kwang Joon& Kim, So Ra& Kang, Eun Seok& Cha, Bong Soo…[et al.]. 2015. Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA1c with Time. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055979
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yoon, Hye-jin…[et al.]. Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA1c with Time. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1055979
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yoon, Hye-jin& Lee, Yong-ho& Kim, Kwang Joon& Kim, So Ra& Kang, Eun Seok& Cha, Bong Soo…[et al.]. Glycated Albumin Levels in Patients with Type 2 Diabetes Increase Relative to HbA1c with Time. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1055979
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1055979
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر