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Single-Fraction Radiotherapy for CD30+ Lymphoproliferative Disorders
المؤلفون المشاركون
Gentile, Michelle S.
Martinez-Escala, Maria Estela
Thomas, Tarita O.
Guitart, Joan
Rosen, Steven
Kuzel, Timothy
Mittal, Bharat B.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-04
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Objectives.
CD30+ lymphoproliferative disorder is a rare variant of cutaneous T-cell lymphoma.
Sustained complete response following first-line treatments is rare.
This retrospective review evaluates the response of refractory or recurrent lesions to palliative radiation therapy.
Methods.
The records of 6 patients with 12 lesions, treated with radiation therapy, were reviewed.
All patients received previous first-line treatments.
Patients with clinical and pathological evidence of symptomatic CD30+ lymphoproliferative disorder, with no history of other cutaneous T-cell lymphoma variants, and with no prior radiation therapy to the index site were included.
Results.
The median age of patients was 50.5 years (range, 15–83 years).
Median size of the treated lesions was 2.5 cm (range, 2–7 cm).
Four sites were treated with a single fraction of 750–800 cGy (n=3) and 8 sites were treated with 4000–4500 cGy in 200–250 cGy fractions (n=3).
Radiation therapy was administered with electrons and bolus.
Median follow-up was 113 months (range, 16–147 months).
For all sites, there was 100% complete response with acute grade 1-2 dermatitis.
Conclusions.
For recurrent and symptomatic radiation-naïve CD30+ lymphoproliferative disorder lesions, palliative radiation therapy shows excellent response.
A single fraction of 750–800 cGy is as effective as a multifractionated course and more convenient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gentile, Michelle S.& Martinez-Escala, Maria Estela& Thomas, Tarita O.& Guitart, Joan& Rosen, Steven& Kuzel, Timothy…[et al.]. 2015. Single-Fraction Radiotherapy for CD30+ Lymphoproliferative Disorders. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1056201
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gentile, Michelle S.…[et al.]. Single-Fraction Radiotherapy for CD30+ Lymphoproliferative Disorders. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1056201
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gentile, Michelle S.& Martinez-Escala, Maria Estela& Thomas, Tarita O.& Guitart, Joan& Rosen, Steven& Kuzel, Timothy…[et al.]. Single-Fraction Radiotherapy for CD30+ Lymphoproliferative Disorders. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1056201
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056201
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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