The Effect of Phospholipids (Surfactant)‎ on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model

المؤلفون المشاركون

Dabak, T. Kursat
Sertkaya, Omer
Acar, Nuray
Donmez, B. Ozgur
Ustunel, Ismail

المصدر

BioMed Research International

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-05-25

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

Adhesion of the tendon is a major challenge for the orthopedic surgeon during tendon repair.

Manipulation of biological environment is one of the concepts to prevent adhesion.

Lots of biochemicals have been studied for this purpose.

We aimed to determine the effect of phospholipids on adhesion and biomechanical properties of tendon in an animal tendon repair model.

Seventy-two Wistar rats were divided into 4 groups.

Achilles tendons of rats were cut and repaired.

Phospholipids were applied at two different dosages.

Tendon adhesion was determined histopathologically and biomechanical test was performed.

At macroscopic evaluation of adhesion, there are statistically significant differences between multiple-dose phospholipid injection group and Control group and also hyaluronic acid group and Control group (p<0.008).

At microscopic evaluation of adhesion, there was no statistically significant difference (p>0.008).

Ultimate strength was highest at hyaluronic acid injection group and lowest at multiple-dose phospholipid injection group.

Single-dose phospholipids (surfactant) application may have a beneficial effect on the tendon adhesion.

Although multiple applications of phospholipids seem the most effective regime to reduce the tendon adhesion among groups, it deteriorated the biomechanical properties of tendon.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Dabak, T. Kursat& Sertkaya, Omer& Acar, Nuray& Donmez, B. Ozgur& Ustunel, Ismail. 2015. The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056395

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Dabak, T. Kursat…[et al.]. The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056395

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Dabak, T. Kursat& Sertkaya, Omer& Acar, Nuray& Donmez, B. Ozgur& Ustunel, Ismail. The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056395

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1056395