The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model
Joint Authors
Dabak, T. Kursat
Sertkaya, Omer
Acar, Nuray
Donmez, B. Ozgur
Ustunel, Ismail
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Adhesion of the tendon is a major challenge for the orthopedic surgeon during tendon repair.
Manipulation of biological environment is one of the concepts to prevent adhesion.
Lots of biochemicals have been studied for this purpose.
We aimed to determine the effect of phospholipids on adhesion and biomechanical properties of tendon in an animal tendon repair model.
Seventy-two Wistar rats were divided into 4 groups.
Achilles tendons of rats were cut and repaired.
Phospholipids were applied at two different dosages.
Tendon adhesion was determined histopathologically and biomechanical test was performed.
At macroscopic evaluation of adhesion, there are statistically significant differences between multiple-dose phospholipid injection group and Control group and also hyaluronic acid group and Control group (p<0.008).
At microscopic evaluation of adhesion, there was no statistically significant difference (p>0.008).
Ultimate strength was highest at hyaluronic acid injection group and lowest at multiple-dose phospholipid injection group.
Single-dose phospholipids (surfactant) application may have a beneficial effect on the tendon adhesion.
Although multiple applications of phospholipids seem the most effective regime to reduce the tendon adhesion among groups, it deteriorated the biomechanical properties of tendon.
American Psychological Association (APA)
Dabak, T. Kursat& Sertkaya, Omer& Acar, Nuray& Donmez, B. Ozgur& Ustunel, Ismail. 2015. The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056395
Modern Language Association (MLA)
Dabak, T. Kursat…[et al.]. The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056395
American Medical Association (AMA)
Dabak, T. Kursat& Sertkaya, Omer& Acar, Nuray& Donmez, B. Ozgur& Ustunel, Ismail. The Effect of Phospholipids (Surfactant) on Adhesion and Biomechanical Properties of Tendon: A Rat Achilles Tendon Repair Model. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056395
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056395