Prognostic Value of Classifying Parapharyngeal Extension in Nasopharyngeal Carcinoma Based on Magnetic Resonance Imaging
المؤلفون المشاركون
Zhang, Guo-Yi
Wang, Yue-Jian
Chen, Xiang-Ping
Xu, Tao
Wei, Wei-Hong
Hu, Xue-Feng
Huang, Guo-Sen
Zhou, Miao-Miao
Huang, Ze-Li
Huang, Ying
Liu, Lizhi
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-03-26
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Purpose.
To subclassify parapharyngeal extension in nasopharyngeal carcinoma (NPC) and investigate its prognostic value and staging categories based on magnetic resonance imaging (MRI).
Methods and Materials.
Data from 1504 consecutive NPC patients treated with definitive-intent radiotherapy were analyzed retrospectively.
Sites of parapharyngeal extension were defined by MRI.
Overall survival (OS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) were calculated by the Kaplan-Meier method and compared with the log-rank test.
Hazard consistency and hazard discrimination were determined by multivariate analysis with Cox proportional hazards models.
Results.
1104 patients (73.4%) had parapharyngeal extension; 1.7–63.8% had involvement of various anatomic sites.
The hazard ratio for death was significantly higher with extensive parapharyngeal extension (lateral pterygoid muscle of masticator space and beyond or parotid space) than with mild extension (medial pterygoid muscle of masticator space, or carotid, prestyloid, and prevertebral or retropharyngeal space).
OS, LRFS, and DMFS with extensive parapharyngeal extension were similar to those in T4 disease; OS, LRFS, and DMFS with mild parapharyngeal extension were significantly higher than in those T3 disease (all P ≤ 0.015).
Conclusions.
Parapharyngeal extension in NPC should be subclassified as mild or extensive, which should be regarded as stages T2 and T4 diseases, respectively.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Guo-Yi& Huang, Ying& Hu, Xue-Feng& Chen, Xiang-Ping& Xu, Tao& Liu, Lizhi…[et al.]. 2015. Prognostic Value of Classifying Parapharyngeal Extension in Nasopharyngeal Carcinoma Based on Magnetic Resonance Imaging. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056612
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Guo-Yi…[et al.]. Prognostic Value of Classifying Parapharyngeal Extension in Nasopharyngeal Carcinoma Based on Magnetic Resonance Imaging. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1056612
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Guo-Yi& Huang, Ying& Hu, Xue-Feng& Chen, Xiang-Ping& Xu, Tao& Liu, Lizhi…[et al.]. Prognostic Value of Classifying Parapharyngeal Extension in Nasopharyngeal Carcinoma Based on Magnetic Resonance Imaging. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056612
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056612
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر