A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results

المؤلفون المشاركون

Karakitsos, Petros
Margari, Niki
Terzakis, Emmanouil
Panayiotides, Ioannis
Koureas, Nikolaos
Bilirakis, Evripidis
Chrelias, Charalampos
Pappas, Asimakis
Pouliakis, Abraham
Aga, Evangelia
Kottaridi, Christine
Spathis, Aris

المصدر

BioMed Research International

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-10-04

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الطب البشري

الملخص EN

Endometrial cancer is the most common malignancy of the female genital tract while aberrant DNA methylation seems to play a critical role in endometrial carcinogenesis.

Galanin’s expression has been involved in many cancers.

We developed a new pyrosequencing assay that quantifies DNA methylation of galanin’s receptor-1 (GALR1).

In this study, the preliminary results indicate that pyrosequencing methylation analysis of GALR1 promoter can be a useful ancillary marker to cytology as the histological status can successfully predict.

This marker has the potential to lead towards better management of women with endometrial lesions and eventually reduce unnecessary interventions.

In addition it can provide early warning for women with negative cytological result.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Kottaridi, Christine& Koureas, Nikolaos& Margari, Niki& Terzakis, Emmanouil& Bilirakis, Evripidis& Pappas, Asimakis…[et al.]. 2015. A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056641

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Kottaridi, Christine…[et al.]. A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056641

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Kottaridi, Christine& Koureas, Nikolaos& Margari, Niki& Terzakis, Emmanouil& Bilirakis, Evripidis& Pappas, Asimakis…[et al.]. A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056641

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1056641