A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results
Joint Authors
Karakitsos, Petros
Margari, Niki
Terzakis, Emmanouil
Panayiotides, Ioannis
Koureas, Nikolaos
Bilirakis, Evripidis
Chrelias, Charalampos
Pappas, Asimakis
Pouliakis, Abraham
Aga, Evangelia
Kottaridi, Christine
Spathis, Aris
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Endometrial cancer is the most common malignancy of the female genital tract while aberrant DNA methylation seems to play a critical role in endometrial carcinogenesis.
Galanin’s expression has been involved in many cancers.
We developed a new pyrosequencing assay that quantifies DNA methylation of galanin’s receptor-1 (GALR1).
In this study, the preliminary results indicate that pyrosequencing methylation analysis of GALR1 promoter can be a useful ancillary marker to cytology as the histological status can successfully predict.
This marker has the potential to lead towards better management of women with endometrial lesions and eventually reduce unnecessary interventions.
In addition it can provide early warning for women with negative cytological result.
American Psychological Association (APA)
Kottaridi, Christine& Koureas, Nikolaos& Margari, Niki& Terzakis, Emmanouil& Bilirakis, Evripidis& Pappas, Asimakis…[et al.]. 2015. A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056641
Modern Language Association (MLA)
Kottaridi, Christine…[et al.]. A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056641
American Medical Association (AMA)
Kottaridi, Christine& Koureas, Nikolaos& Margari, Niki& Terzakis, Emmanouil& Bilirakis, Evripidis& Pappas, Asimakis…[et al.]. A Pyrosequencing Assay for the Quantitative Methylation Analysis of GALR1 in Endometrial Samples: Preliminary Results. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056641
