Surgical Modification of the Murine Calvaria Osteolysis Model
المؤلفون المشاركون
Al-quhali, Ali Mohammed
Sun, Yu
Bai, Xizhuang
Jin, Zhe
Yu, Guibo
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-03
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
The murine calvaria model has been adopted for evaluation of osteolysis and inflammation induced by polyethylene (PE) or metal wear debris.
However, this model suffers from several complications.
The purpose of our study is to introduce a surgical modification with lower complication rates, thus providing more accurate results.
Forty C57/BL6 mice were divided into two groups, both receiving polyethylene particles.
Surgical modifications were performed in group 1, and group 2 underwent traditional surgeries.
The incidence of fluid leakage was recorded on the operative day.
Curst formation, wound dehiscence, and bone exposure were recorded on day 7.
Histological osteolysis was demonstrated by HE staining of tissue slices.
Micro-CT was used for quantifying evaluation of osteolysis in two groups.
Intraoperative fluid leakage was significantly reduced in group 1.
Postoperative crust formation, wound dehiscence, and bone exposure were also significantly decreased in group 1.
HE staining results revealed obvious osteolysis in group 1 and more obvious osteolysis in group 2.
Bone volume fraction (BVF) was (0.32 ± 0.03) in group 1 compared to group 2 (0.24 ± 0.05).
Bone mineral density (BMD) was (1.11 ± 0.03) in group 1 compared to group 2 (1.01 ± 0.02).
Surgical modifications provide a reliable way for establishment of the murine calvaria osteolysis model.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Al-quhali, Ali Mohammed& Sun, Yu& Bai, Xizhuang& Jin, Zhe& Yu, Guibo. 2015. Surgical Modification of the Murine Calvaria Osteolysis Model. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1056781
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Al-quhali, Ali Mohammed…[et al.]. Surgical Modification of the Murine Calvaria Osteolysis Model. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1056781
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Al-quhali, Ali Mohammed& Sun, Yu& Bai, Xizhuang& Jin, Zhe& Yu, Guibo. Surgical Modification of the Murine Calvaria Osteolysis Model. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1056781
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056781
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر