Cortical Structural Connectivity Alterations in Primary Insomnia: Insights from MRI-Based Morphometric Correlation Analysis
المؤلفون المشاركون
Guan, Min
Zhao, Lu
Wang, Enfeng
Zhang, Xiaoqi
Karama, Sherif
Khundrakpam, Budhachandra
Zhang, Hongju
Wang, Meiyun
Cheng, Jingliang
Shi, Dapeng
Evans, Alan C.
Li, Yongli
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-23، 23ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-10-11
دولة النشر
مصر
عدد الصفحات
23
التخصصات الرئيسية
الملخص EN
The etiology and maintenance of insomnia are proposed to be associated with increased cognitive and physiological arousal caused by acute stressors and associated cognitive rumination.
A core feature of such hyperarousal theory of insomnia involves increased sensory processing that interferes with the onset and maintenance of sleep.
In this work, we collected structural magnetic resonance imaging data from 35 patients with primary insomnia and 35 normal sleepers and applied structural covariance analysis to investigate whether insomnia is associated with disruptions in structural brain networks centered at the sensory regions (primary visual, primary auditory, and olfactory cortex).
As expected, insomnia patients showed increased structural covariance in cortical thickness between sensory and motor regions.
We also observed trends of increased covariance between sensory regions and the default-mode network, and the salience network regions, and trends of decreased covariance between sensory regions and the frontoparietal working memory network regions, in insomnia patients.
The observed changes in structural covariance tended to correlated with poor sleep quality.
Our findings support previous functional neuroimaging studies and provide novel insights into variations in brain network configuration that may be involved in the pathophysiology of insomnia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhao, Lu& Wang, Enfeng& Zhang, Xiaoqi& Karama, Sherif& Khundrakpam, Budhachandra& Zhang, Hongju…[et al.]. 2015. Cortical Structural Connectivity Alterations in Primary Insomnia: Insights from MRI-Based Morphometric Correlation Analysis. BioMed Research International،Vol. 2015, no. 2015, pp.1-23.
https://search.emarefa.net/detail/BIM-1056847
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhao, Lu…[et al.]. Cortical Structural Connectivity Alterations in Primary Insomnia: Insights from MRI-Based Morphometric Correlation Analysis. BioMed Research International No. 2015 (2015), pp.1-23.
https://search.emarefa.net/detail/BIM-1056847
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhao, Lu& Wang, Enfeng& Zhang, Xiaoqi& Karama, Sherif& Khundrakpam, Budhachandra& Zhang, Hongju…[et al.]. Cortical Structural Connectivity Alterations in Primary Insomnia: Insights from MRI-Based Morphometric Correlation Analysis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-23.
https://search.emarefa.net/detail/BIM-1056847
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056847
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر