Rheology as a Tool to Predict the Release of Alpha-Lipoic Acid from Emulsions Used for the Prevention of Skin Aging
المؤلفون المشاركون
Ribeiro, Helena M.
Corrêa, M. A.
Isaac, Vera Lucia Borges
Chiari-Andréo, Bruna Galdorfini
Marto, Joana Marques
Moraes, Jemima Daniela Dias
Leone, Beatriz Alves
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-12-16
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The availability of an active substance through the skin depends basically on two consecutive steps: the release of this substance from the vehicle and its subsequent permeation through the skin.
Hence, studies on the specific properties of vehicles, such as their rheological behavior, are of great interest in the field of dermatological products.
Recent studies have shown the influence of the rheological features of a vehicle on the release of drugs and active compounds from the formulation.
In this context, the aim of this study was to evaluate the influence of the rheological features of two different emulsion formulations on the release of alpha-lipoic acid.
Alpha-lipoic acid (ALA) was chosen for this study because of its antioxidant characteristics, which could be useful for the prevention of skin diseases and aging.
The rheological and mechanical behavior and the in vitro release profile were assayed.
The results showed that rheological features, such as viscosity, thixotropy, and compliance, strongly influenced the release of ALA from the emulsion and that the presence of a hydrophilic polymer in one of the emulsions was an important factor affecting the rheology and, therefore, the release of ALA.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Isaac, Vera Lucia Borges& Chiari-Andréo, Bruna Galdorfini& Marto, Joana Marques& Moraes, Jemima Daniela Dias& Leone, Beatriz Alves& Corrêa, M. A.…[et al.]. 2015. Rheology as a Tool to Predict the Release of Alpha-Lipoic Acid from Emulsions Used for the Prevention of Skin Aging. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056852
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Isaac, Vera Lucia Borges…[et al.]. Rheology as a Tool to Predict the Release of Alpha-Lipoic Acid from Emulsions Used for the Prevention of Skin Aging. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1056852
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Isaac, Vera Lucia Borges& Chiari-Andréo, Bruna Galdorfini& Marto, Joana Marques& Moraes, Jemima Daniela Dias& Leone, Beatriz Alves& Corrêa, M. A.…[et al.]. Rheology as a Tool to Predict the Release of Alpha-Lipoic Acid from Emulsions Used for the Prevention of Skin Aging. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056852
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056852
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر