Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges

المؤلفون المشاركون

Tolliver, Larry M.
Aronstam, Robert S.
Huang, Yue-wern
Lee, Han-Jung

المصدر

BioMed Research International

العدد

المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-16، 16ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2015-03-26

دولة النشر

مصر

عدد الصفحات

16

التخصصات الرئيسية

الطب البشري

الملخص EN

Many viral and nonviral systems have been developed to aid delivery of biologically active molecules into cells.

Among these, cell-penetrating peptides (CPPs) have received increasing attention in the past two decades for biomedical applications.

In this review, we focus on opportunities and challenges associated with CPP delivery of nucleic acids and nanomaterials.

We first describe the nature of versatile CPPs and their interactions with various types of cargoes.

We then discuss in vivo and in vitro delivery of nucleic acids and nanomaterials by CPPs.

Studies on the mechanisms of cellular entry and limitations in the methods used are detailed.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Huang, Yue-wern& Lee, Han-Jung& Tolliver, Larry M.& Aronstam, Robert S.. 2015. Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges. BioMed Research International،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056924

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Huang, Yue-wern…[et al.]. Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges. BioMed Research International No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1056924

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Huang, Yue-wern& Lee, Han-Jung& Tolliver, Larry M.& Aronstam, Robert S.. Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056924

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1056924