Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges
Joint Authors
Tolliver, Larry M.
Aronstam, Robert S.
Huang, Yue-wern
Lee, Han-Jung
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-26
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Many viral and nonviral systems have been developed to aid delivery of biologically active molecules into cells.
Among these, cell-penetrating peptides (CPPs) have received increasing attention in the past two decades for biomedical applications.
In this review, we focus on opportunities and challenges associated with CPP delivery of nucleic acids and nanomaterials.
We first describe the nature of versatile CPPs and their interactions with various types of cargoes.
We then discuss in vivo and in vitro delivery of nucleic acids and nanomaterials by CPPs.
Studies on the mechanisms of cellular entry and limitations in the methods used are detailed.
American Psychological Association (APA)
Huang, Yue-wern& Lee, Han-Jung& Tolliver, Larry M.& Aronstam, Robert S.. 2015. Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges. BioMed Research International،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056924
Modern Language Association (MLA)
Huang, Yue-wern…[et al.]. Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges. BioMed Research International No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1056924
American Medical Association (AMA)
Huang, Yue-wern& Lee, Han-Jung& Tolliver, Larry M.& Aronstam, Robert S.. Delivery of Nucleic Acids and Nanomaterials by Cell-Penetrating Peptides: Opportunities and Challenges. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1056924
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056924