Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals
المؤلفون المشاركون
Cordeiro, A.
Pereira, S. E.
Saboya, C. J.
Ramalho, A.
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-05-18
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Introduction.
Obesity is represented mainly by abdominal obesity and insulin resistance (IR), both present in most individuals diagnosed with metabolic syndrome (MS).
IR is the key risk factor in the pathogenesis of nonalcoholic fatty liver disease (NAFLD).
Objective.
To relate NAFLD to MS in class III obese individuals.
Methodology.
A descriptive cross-sectional study with class III obese individuals, aged ≥ 20–60 years.
Blood pressure measurement, weight, height, body mass index (BMI), waist circumference (WC) and blood glucose, insulin, high-density lipoprotein cholesterol (HDL-c), and triglycerides data were obtained.
HOMA-IR (homeostatic model assessment insulin resistance) calculation was carried out with a cutoff value of 2.71 for IR evaluation.
The diagnosis of NAFLD was performed by liver biopsy and the diagnosis of MS was performed in accordance with the National Cholesterol Education Program/Adult Treatment Panel III (NCEPATP III).
Results.
Of the 50 individuals evaluated, 86% were women and BMI means were 45.4 ± 3.6 Kg/m2.
The overall individuals had NAFLD, 70% steatosis, and 30% steatohepatitis.
The diagnosis of MS occurred in 56% but showed no significant association with NAFLD (P=0.254).
Triglycerides (178 ± 65.5 mg/dL) and insulin (28.2 ± 22.6 mcU/mL) mean values were significantly higher in steatohepatitis (P=0.002 and P=0.042, resp.) compared to individuals with steatosis.
IR was confirmed in 76% and showed a relationship with NAFLD severity.
Conclusion.
NAFLD was not related to MS; however, MS components, evaluated in isolation, as well as IR, were related to the presence and severity of NAFLD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cordeiro, A.& Pereira, S. E.& Saboya, C. J.& Ramalho, A.. 2015. Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056946
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cordeiro, A.…[et al.]. Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1056946
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cordeiro, A.& Pereira, S. E.& Saboya, C. J.& Ramalho, A.. Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1056946
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1056946
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر