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Synthesis, Characterization, and Antibacterial Activities of Novel Sulfonamides Derived through Condensation of Amino Group Containing Drugs, Amino Acids, and Their Analogs
المؤلفون المشاركون
Abdul Qadir, Muhammad
Ahmed, Mahmood
Iqbal, Muhammad
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-02-24
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Novel sulfonamides were developed and structures of the new products were confirmed by elemental and spectral analysis (FT-IR, ESI-MS, 1HNMR, and 13CNMR).
In vitro, developed compounds were screened for their antibacterial activities against medically important gram (+) and gram (−) bacterial strains, namely, S.
aureus, B.
subtilis, E.
coli, and K.
pneumoniae.
The antibacterial activities have been determined by measuring MIC values (μg/mL) and zone of inhibitions (mm).
Among the tested compounds, it was found that compounds 5a and 9a have most potent activity against E.
coli with zone of inhibition: 31±0.12 mm (MIC: 7.81 μg/mL) and 30±0.12 mm (MIC: 7.81 μg/mL), respectively, nearly as active as ciprofloxacin (zone of inhibition: 32±0.12 mm).
In contrast, all the compounds were totally inactive against the gram (+) B.
subtilis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Abdul Qadir, Muhammad& Ahmed, Mahmood& Iqbal, Muhammad. 2015. Synthesis, Characterization, and Antibacterial Activities of Novel Sulfonamides Derived through Condensation of Amino Group Containing Drugs, Amino Acids, and Their Analogs. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057307
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Abdul Qadir, Muhammad…[et al.]. Synthesis, Characterization, and Antibacterial Activities of Novel Sulfonamides Derived through Condensation of Amino Group Containing Drugs, Amino Acids, and Their Analogs. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057307
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Abdul Qadir, Muhammad& Ahmed, Mahmood& Iqbal, Muhammad. Synthesis, Characterization, and Antibacterial Activities of Novel Sulfonamides Derived through Condensation of Amino Group Containing Drugs, Amino Acids, and Their Analogs. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057307
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057307
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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