![](/images/graphics-bg.png)
The Biocompatibility of Degradable Magnesium Interference Screws: An Experimental Study with Sheep
المؤلفون المشاركون
Szalay, Gabor
Heiss, Christian
Schnettler, Reinhard
Lips, Katrin Susanne
Thormann, Ulrich
Alt, Volker
Heimann, Lydia
Gasquere, Cyrille
Franke, Jörg
المصدر
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-01-31
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
Screws for ligament reconstruction are nowadays mostly made of poly-L-lactide (PLLA).
However, magnesium-based biomaterials are gathering increased interest in this research field because of their good mechanical property and osteoanabolic influence on bone metabolism.
The aim of this pilot study was to evaluate the biocompatibility of an interference screw for ligament reconstruction made of magnesium alloy W4 by diecasting and milling and using different PEO-coatings with calcium phosphates.
PLLA and titanium screws were used as control samples.
The screws were implanted in the femur condyle of the hind leg of a merino sheep.
The observation period was six and twelve weeks and one year.
Histomorphometric, immunohistochemical, immunofluorescence, and molecular biological evaluation were conducted.
Further TEM analysis was done.
In all magnesium screws a clinically relevant gas formation in the vicinity of the biomaterial was observed.
Except for the PLLA and titanium control samples, no screw was fully integrated in the surrounding bone tissue.
Regarding the fabrication process, milling seems to produce less gas liberation and has a better influence on bone metabolism than diecasting.
Coating by PEO with calcium phosphates could not reduce the initial gas liberation but rather reduced the bone metabolism in the vicinity of the biomaterial.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Thormann, Ulrich& Alt, Volker& Heimann, Lydia& Gasquere, Cyrille& Heiss, Christian& Szalay, Gabor…[et al.]. 2015. The Biocompatibility of Degradable Magnesium Interference Screws: An Experimental Study with Sheep. BioMed Research International،Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1057332
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Thormann, Ulrich…[et al.]. The Biocompatibility of Degradable Magnesium Interference Screws: An Experimental Study with Sheep. BioMed Research International No. 2015 (2015), pp.1-15.
https://search.emarefa.net/detail/BIM-1057332
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Thormann, Ulrich& Alt, Volker& Heimann, Lydia& Gasquere, Cyrille& Heiss, Christian& Szalay, Gabor…[et al.]. The Biocompatibility of Degradable Magnesium Interference Screws: An Experimental Study with Sheep. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1057332
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057332
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)