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A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays
المؤلفون المشاركون
Regalia, Giulia
Biffi, Emilia
Ferrigno, G.
Pedrocchi, A.
المصدر
Computational Intelligence and Neuroscience
العدد
المجلد 2015، العدد 2015 (31 ديسمبر/كانون الأول 2015)، ص ص. 1-15، 15ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2015-04-21
دولة النشر
مصر
عدد الصفحات
15
التخصصات الرئيسية
الملخص EN
The collection of good quality extracellular neuronal spikes from neuronal cultures coupled to Microelectrode Arrays (MEAs) is a binding requirement to gather reliable data.
Due to physical constraints, low power requirement, or the need of customizability, commercial recording platforms are not fully adequate for the development of experimental setups integrating MEA technology with other equipment needed to perform experiments under climate controlled conditions, like environmental chambers or cell culture incubators.
To address this issue, we developed a custom MEA interfacing system featuring low noise, low power, and the capability to be readily integrated inside an incubator-like environment.
Two stages, a preamplifier and a filter amplifier, were designed, implemented on printed circuit boards, and tested.
The system is characterized by a low input-referred noise (<1 μV RMS), a high channel separation (>70 dB), and signal-to-noise ratio values of neuronal recordings comparable to those obtained with the benchmark commercial MEA system.
In addition, the system was successfully integrated with an environmental MEA chamber, without harming cell cultures during experiments and without being damaged by the high humidity level.
The devised system is of practical value in the development of in vitro platforms to study temporally extended neuronal network dynamics by means of MEAs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Regalia, Giulia& Biffi, Emilia& Ferrigno, G.& Pedrocchi, A.. 2015. A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays. Computational Intelligence and Neuroscience،Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1057668
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Regalia, Giulia…[et al.]. A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays. Computational Intelligence and Neuroscience No. 2015 (2015), pp.1-15.
https://search.emarefa.net/detail/BIM-1057668
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Regalia, Giulia& Biffi, Emilia& Ferrigno, G.& Pedrocchi, A.. A Low-Noise, Modular, and Versatile Analog Front-End Intended for Processing In Vitro Neuronal Signals Detected by Microelectrode Arrays. Computational Intelligence and Neuroscience. 2015. Vol. 2015, no. 2015, pp.1-15.
https://search.emarefa.net/detail/BIM-1057668
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1057668
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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